Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Sep 28;76(1):132.
doi: 10.1186/s43044-024-00566-3.

Evaluation of right ventricular functions in patients with ischemic cardiomyopathy by speckle-tracking echocardiography

Reham Mohamed Darweesh  1 , Dina Mohamed Yousry Ahmed  2 , Kamal Mahmoud Ahmed  2 , Wafaa Anwar El-Aroussy  1 , Abdalla Amin Elagha  3
Affiliations

Evaluation of right ventricular functions in patients with ischemic cardiomyopathy by speckle-tracking echocardiography

Reham Mohamed Darweesh et al. Egypt Heart J. .

Abstract

Background: It is widely recognized that the right ventricle plays a significant role in the prognosis of numerous diseases. However, the assessment of right ventricular function (RV) has not been given much attention until recently. This study used speckle-tracking echocardiography (STE) to assess RV functions in ischemic cardiomyopathy (ICM) patients.

Results: This study included 74 patients diagnosed with ischemic cardiomyopathy (ICM) and an ejection fraction (EF) of less than 50%. Although all the selected patients had normal RV systolic function by tricuspid annular plane systolic excursion (TAPSE), a considerable percentage of them had subtle RV systolic dysfunction, which could be identified by right ventricular free wall longitudinal strain (RV FWLS) (36.5%) and right ventricular global longitudinal strain (RV GLS) (55.4%). Moreover, the mean RV FWLS was significantly higher than RV GLS (- 20.4 ± 5.08% vs. - 17.5 ± 6.89%), respectively. Advanced left ventricle (LV) adverse remodeling was associated with subtle RV dysfunction. Using multivariate regression analysis, increased E/e' (p = 0.016, CI 1.135-3.423) and RV myocardial performance index (MPI) (p = 0.007, CI 0.000-0.007) were identified as independent factors of impaired RV FWLS with the greatest effectiveness.

Conclusion: When standard RV measures are normal in patients with ICM, RV systolic strain analysis offers an incremental utility to detect subtle abnormalities in RV function, especially in resource-constrained settings where cardiac magnetic resonance (CMR) is not practical.

Keywords: Ischemic cardiomyopathy; Right ventricle; Speckle-tracking echocardiography.

PubMed Disclaimer

Conflict of interest statement

The authors declare that there is no conflict of interest.

Figures

Fig. 1
Fig. 1
The measurement of RV GLS and RV FWLS from apical 4-chamber view. A 60-year-old male patient was considered as having normal RV function by TAPSE (2.1 cm); however, RV GLS was − 12.3% and RV FW PSS was − 17.6%
Fig. 2
Fig. 2
Scatter plots of correlations of RV FWLS to different clinical and echocardiographic parameters
Fig. 3
Fig. 3
Correlation between RV GLS and RV FWLS
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L, Flachskampf FA, Foster E, Goldstein SA, Kuznetsova T, Lancellotti P, Muraru D, Picard MH, Rietzschel ER, Rudski L, Spencer KT, Tsang W, Voigt JU (2015) Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr 28(1):1–39. 10.1016/j.echo.2014.10.003 - PubMed
    1. Antoni ML, Scherptong RW, Atary JZ, Boersma E, Holman ER, van der Wall EE, Schalij MJ, Bax JJ (2010) Prognostic value of right ventricular function in patients after acute myocardial infarction treated with primary percutaneous coronary intervention. Circ Cardiovasc Imaging 3(3):264–271. 10.1161/circimaging.109.914366 - PubMed
    1. Borges AC, Knebel F, Eddicks S, Panda A, Schattke S, Witt C, Baumann G (2006) Right ventricular function assessed by two-dimensional strain and tissue Doppler echocardiography in patients with pulmonary arterial hypertension and effect of vasodilator therapy. Am J Cardiol 98(4):530–534. 10.1016/j.amjcard.2006.02.060 - PubMed
    1. Teske AJ, Prakken NH, De Boeck BW, Velthuis BK, Martens EP, Doevendans PA, Cramer MJ (2009) Echocardiographic tissue deformation imaging of right ventricular systolic function in endurance athletes. Eur Heart J 30(8):969–977. 10.1093/eurheartj/ehp040 - PubMed
    1. Prakasa KR, Wang J, Tandri H, Dalal D, Bomma C, Chojnowski R, James C, Tichnell C, Russell S, Judge D, Corretti M, Bluemke D, Calkins H, Abraham TP (2007) Utility of tissue Doppler and strain echocardiography in arrhythmogenic right ventricular dysplasia/cardiomyopathy. Am J Cardiol 100(3):507–512. 10.1016/j.amjcard.2007.03.053 - PubMed

LinkOut - more resources