Review
doi: 10.1007/BF00262414.
m-AMSA and PALA: two new agents in cancer chemotherapy
- PMID: 393427
- DOI: 10.1007/BF00262414
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Review
m-AMSA and PALA: two new agents in cancer chemotherapy
Cancer Chemother Pharmacol.
1979.
Abstract
4'-(9-Acridinylamino)methanesulfon-m-anisidide (m-AMSA) and N-(phosphonacetyl)-L-aspartate (PALA) are two new anticancer agents that have been recently introduced into clinical investigation. This review summarizes the preclinical information that has accumulated with these compounds as well as the very preliminary data presently available from early clinical trials. This information indicates the promising potential of m-AMSA and PALA in the treatment of cancer.
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