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Review
. 1979;3(3):135-41.
doi: 10.1007/BF00262414.

m-AMSA and PALA: two new agents in cancer chemotherapy

M Rozencweig, D D Von Hoff, R L Cysyk, F M Muggia
Review

m-AMSA and PALA: two new agents in cancer chemotherapy

M Rozencweig et al. Cancer Chemother Pharmacol. 1979.

Abstract

4'-(9-Acridinylamino)methanesulfon-m-anisidide (m-AMSA) and N-(phosphonacetyl)-L-aspartate (PALA) are two new anticancer agents that have been recently introduced into clinical investigation. This review summarizes the preclinical information that has accumulated with these compounds as well as the very preliminary data presently available from early clinical trials. This information indicates the promising potential of m-AMSA and PALA in the treatment of cancer.

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References

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