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. 2024 Sep 13:12:1461300.
doi: 10.3389/fpubh.2024.1461300. eCollection 2024.

Association between weight-adjusted waist circumference index and depression in older patients with hypertension: a study based on NHANES 2007-2016

Yi Niu  1 , Yuqin Sun  1 , Yijie Xie  2 , Shun Yu  3
Affiliations

Association between weight-adjusted waist circumference index and depression in older patients with hypertension: a study based on NHANES 2007-2016

Yi Niu et al. Front Public Health. .

Abstract

Objective: Our aim was to assess the relationship between weight-adjusted waist circumference index (WWI) and the prevalence of depression in older adult hypertensive patients in the United States.

Methods: We selected individuals from the National Health and Nutrition Examination Survey (NHANES) database from 2007 to 2016 and used logistic regression analyses, subgroup analyses, and dose-response curves to assess the associations between the WWI index and the prevalence of depression in older hypertensive patients with age, sex, and BMI.

Results: A total of 4,228 participants aged ≥60 years with hypertension were included in our study; 364 patients were assessed for depression. After correction for confounders, each unit increase in WWI increased the risk of depression in older hypertensive patients by 19% (OR = 1.19, 95% CI: 0.99, 1.43). Dose-response curves showed that the WWI index was positively associated with the prevalence of depression in older hypertensive patients when the WWI index was ≥11.6. Based on subgroup analyses, this association was particularly pronounced in individuals ≥70 years of age, women, and individuals with a BMI of 25 or greater.

Conclusion: Higher WWI scores were positively associated with the prevalence of depression in older hypertensive patients and correlated with gender, age and BMI. This is notable, although a causal relationship cannot be established at this time.

Keywords: NHANES; WWI index; cross-sectional study; depression; hypertension in the older adult.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Flowchart for the selection of eligible participants.
Figure 2
Figure 2
Density, dose–response relationship between the WWI index and the prevalence of depression in older adult hypertensive patients. The area between the upper and lower dashed lines is indicated as the 95% CI. Each point shows the magnitude of the WWI index and is joined to form a continuous line. Adjustments were made for all covariates except effect modifiers (model 4).
Figure 3
Figure 3
Subgroup regression analysis between the WWI index and the prevalence of hypertensive depression in the older adult (fully adjusted model 4).
See this image and copyright information in PMC

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