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. 2024 Sep 30;5(1):107.
doi: 10.1186/s43058-024-00645-1.

Pre-exposure Prophylaxis (PrEP) implementation among latino MSM: a qualitative scoping review of implementation determinants and change methods

Juan Pablo Zapata  1   2 , Alithia Zamantakis  3   4 , Artur Queiroz  5 , James L Merle  6 , Nanette Benbow  3   4 , Brian Mustanski  3   4   7   8
Affiliations

Pre-exposure Prophylaxis (PrEP) implementation among latino MSM: a qualitative scoping review of implementation determinants and change methods

Juan Pablo Zapata et al. Implement Sci Commun. .

Abstract

Introduction: The increasing rates of HIV among Latino men who have sex with men (MSM) necessitate innovative and rigorous studies to evaluate prevention and treatment strategies. Pre-exposure prophylaxis (PrEP) is a highly effective tool in preventing HIV acquisition and plays a crucial role in the Ending the HIV Epidemic in the U.S. initiative. However, there is a scarcity of PrEP research specifically focused on Latino MSM, and the factors influencing its implementation remain largely unknown.

Methods: To address this gap, we conducted a comprehensive review exploring the determinants (barriers and facilitators) of PrEP implementation among Latino MSM, as well as the change methods (implementation strategies and adjunctive interventions) that have been evaluated to promote its adoption. Our review encompassed 43 peer-reviewed articles examining determinants and four articles assessing change methods. Determinants were coded using the updated Consolidated Framework for Implementation Research (CFIR 2.0) to understand the multilevel barriers and facilitators associated with implementation.

Results: The majority of research has focused on PrEP recipients (i.e., patients), primarily examining their awareness and willingness to use PrEP. Fewer studies have explored the factors influencing clinicians and service delivery systems. Additionally, the evaluation of change methods to enhance clinician adoption and adherence to PrEP and recipient adherence to PrEP has been limited.

Conclusion: It is evident that there is a need for culturally adapted strategies tailored specifically for Latino MSM, as the current literature remains largely unexplored in this regard. By incorporating principles from implementation science, we can gain a clearer understanding of the knowledge, skills, and roles necessary for effective cultural adaptations. Future research should emphasize factors influencing implementation from a clinician standpoint and focus on innovative change methods to increase PrEP awareness, reach, adoption, and sustained adherence among Latino MSM.

Keywords: Adjunctive Interventions; Barriers; Consolidated Framework for Implementation Research; Determinants; Facilitators; Implementation Science; Implementation Strategies; Latino MSM; Pre-exposure Prophylaxis.

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Conflict of interest statement

The authors have no relevant financial or non-financial interests to disclose.

Figures

Fig. 1
Fig. 1
PRISMA-ScR Latino scoping review
See this image and copyright information in PMC

References

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    1. Zapata JP, Avila AA, Hurtado M, Aubin ES, Rodriguez-Diaz CE, Robles G. Stakeholders’ perspectives about cultural strategies to support PrEP for latino sexual minority men. AIDS Educ Prev. 2023;35(3):185–200. - PubMed
    1. Eisinger RW, Fauci AS. Ending the global HIV Epidemic begins at the Individual National Level: an update from the United States. China CDC Wkly. 2020;2(39):764. - PMC - PubMed

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