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Comparative Study
. 1985 Sep;28(3):461-3.
doi: 10.1128/AAC.28.3.461.

In vitro activity of Ro 15-8074, a new oral cephalosporin, against Neisseria gonorrhoeae

W S Ng, P Y Chau, Y K Leung, P C Wong
Comparative Study

In vitro activity of Ro 15-8074, a new oral cephalosporin, against Neisseria gonorrhoeae

W S Ng et al. Antimicrob Agents Chemother. 1985 Sep.

Abstract

Ro 15-8074, a new cephalosporin the pivaloyloxymethylester of which (Ro 15-8075) is orally absorbable, showed greater in vitro activity than cefaclor against 48 Neisseria gonorrhoeae strains, including 25 penicillinase-producing strains. Unlike cefaclor, Ro 15-8074 was unaffected by increase in inoculum size, and it exhibited a remarkable stability against gonococcal beta-lactamase hydrolysis.

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References

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