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. 2025 Jan 1;44(1):54-57.
doi: 10.1097/INF.0000000000004558. Epub 2024 Oct 1.

Cytokine Profile in Children Following SARS-CoV-2 Infection: Preliminary Findings

Danilo Buonsenso  1   2   3 , Anna Camporesi  4 , Gabriele Di Sante  5 , Michela Sali  6   7 , Maria Del Carmen Pereyra Boza  6 , Rosa Morello  1 , Piero Valentini  1 , Francesca Raffaelli  8 , Lucie Rodriguez  9 , Laura Gonzalez  9 , Anette Johnsson  9 , Constantin Habimana Mugabo  9 , Tadepally Lakshmikanth  9 , Petter Brodin  9   10
Affiliations

Cytokine Profile in Children Following SARS-CoV-2 Infection: Preliminary Findings

Danilo Buonsenso et al. Pediatr Infect Dis J. .

Abstract

We provide preliminary evidence that, also in children, Long coronavirus disease (COVID) may be characterized by a proinflammatory signature. Ten Long COVID patients, 7 convalescent subjects after COVID infection and 4 healthy controls were enrolled. When adjusted for sex, children with long COVID had statistically significant differences in the levels of Flt3L, CD5, uPA, CCL23, CD40 and TGFα. When adjusted for age, CCL23 levels remained statistically significant.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

Figures

FIGURE 1.
FIGURE 1.
Cytokine expression by COVID‐19 status. A–G: Levels of different proteins in the 3 groups. A: Cytokine expression by COVID-19 status. B: Cytokine expression corrected by sex.
See this image and copyright information in PMC

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