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. 2024 Oct 1;14(1):169.
doi: 10.1038/s41408-024-01151-2.

The triple A (AAA) model globally recapitulates adverse outcomes in essential thrombocythemia

Luca Tosoni  1 , Gian Luca Morelli  1 , Gaia Tomadini  1 , Davide Lazzarotto  1 , Carla Filì  1 , Erica Simeone  1 , Maria Elena Zannier  1 , Chiara Callegari  1 , Matteo Fanin  1 , Giulia Battaglia  1 , Melissa Bergnach  1 , Daniela Damiani  1   2 , Renato Fanin  1   2 , Mario Tiribelli  3   4
Affiliations

The triple A (AAA) model globally recapitulates adverse outcomes in essential thrombocythemia

Luca Tosoni et al. Blood Cancer J. .
No abstract available

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1. Outomes according to AAA risk.
A OS according to AAA risk. 10-year OS was 100% (CI95: 100-100), 95.0% (CI95: 90.0–100), 85.6 (CI95: 72.6–100) and 68.3 (CI95: 49.0–95.3) in L (blue), Int-1 (red), Int-2 (green) and H (azure) risk classes, respectively. Figure 1B TFS according to AAA risk. 10-year TFS was 98,5% (IC95: 95,5–100), 87,8% (IC95: 80,5–95,8), 83,0 (IC95: 68,1–100) and 43,8 (IC95: 24,5–78,5) in L (blue), Int-1 (red), Int-2 (green) and H (azure) risk classes, respectively. Figure 1C MB-free survival according to AAA risk. 10-year MB free survival was 100% (IC95: 100–100), 96,6% (IC95: 92,7–100), 96,9 (IC95: 91,0–100) and 83,7 (IC95: 66,5–100) in L (blue), Int-1 (red), Int-2 (green) and H (azure) risk classes, respectively. Figure 1D. EFS according to AAA risk. 10-year EFS was 96,2% (IC95: 91,0–100), 79,7% (IC95: 71,1–89,4), 70,9 (IC95: 53,9–93,3) and 34,6 (IC95: 18,1–66,2) in L (blue), Int-1 (red), Int-2 (green) and H (azure) risk classes, respectively.
See this image and copyright information in PMC

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