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Comparative Study
. 2024 Oct 1;19(1):570.
doi: 10.1186/s13019-024-03057-3.

Superior long-term patency of no-touch vein graft compared to conventional vein grafts in over 1500 consecutive patients

Gabriele Ferrari  1   2 , Richard Loayza  3 , Ava Azari  3 , Håkan Geijer  4 , Yang Cao  5 , Roland Carlsson  6 , Leif Bojö  7 , Ninos Samano  3 , Domingos Souza  3
Affiliations
Comparative Study

Superior long-term patency of no-touch vein graft compared to conventional vein grafts in over 1500 consecutive patients

Gabriele Ferrari et al. J Cardiothorac Surg. .

Abstract

Objectives: To evaluate the long-term angiographic patency of saphenous vein grafts (SVG) harvested using the no-touch technique compared to the conventional technique.

Methods: This was a single-center, retrospective, cohort study. The inclusion criteria were individuals who underwent a CABG (coronary artery bypass grafting) between January 1995 and July 2020, and who successively needed a clinically-driven angiography. The primary endpoint was long-term patency. The secondary endpoints were differences in patency based on sub-group analysis (single vs. sequential graft, divided by target vessel).

Results: The study included 1520 individuals (618 no-touch, 825 conventional and 77 arterial grafts). The mean clinical follow-up time was 8.4 years ± 5.5 years. The patency per patient was 70.7% in the no-touch grafts vs. 46.7% in the conventional grafts (p < 0.001, OR = 2.8). The graft patency was 75.9% in the no-touch grafts vs. 62.8% in the conventional grafts (p < 0.001, OR = 1.8).

Conclusions: The no-touch vein grafts were associated with statistically significantly higher patency at long-term compared to the conventional grafts.

Clinical trial registration: NCT04656366, 7 December 2020.

Keywords: coronary artery bypass graft; major adverse cardiac events; no-touch; patency; saphenous vein; stent.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
STROBE flowchart of the individuals included in the study A: arterial graft alone; C: conventional graft; CABG: coronary artery bypass grafting; NT: no-touch graft; PCI: percutaneous coronary intervention; SVG: saphenous vein graft
See this image and copyright information in PMC

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