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Comparative Study
. 2024 Sep 30:22:eAO0562.
doi: 10.31744/einstein_journal/2024AO0562. eCollection 2024.

Impact of chronic illness caused by chikungunya fever on quality of life and functionality

Jéssica Isabelle Santos Dutra  1 , Marcelo Cardoso de Souza  2 , Caio Alano Almeida Lins  1 , Anna Cecília Queiroz de Medeiros  1
Affiliations
Comparative Study

Impact of chronic illness caused by chikungunya fever on quality of life and functionality

Jéssica Isabelle Santos Dutra et al. Einstein (Sao Paulo). .

Abstract

Background: Chikungunya fever compromises the functionality and quality of life in the affected individuals, even one year after the acute phase of the disease. Chronically affected people experience direct impairment in performing daily activities, along with a risk of developing other morbidities.

Background: ◼ Even after a year, chikungunya fever-affected people experience damage to their physical and mental health.

Background: ◼ Positive screening for depression risk was 13.5 times more likely in chronically affected.

Background: ◼ Patients with chronic chikungunya fever had a 76 times higher risk of walking impairments.

Objective: To evaluate the impact of chronic illness caused by chikungunya fever on the quality of life and functionality of affected individuals.

Methods: A cross-sectional and comparative study was conducted in which two groups were investigated: a Chikungunya Group comprising 25 patients with chronic fever screened after 1 year of illness via a telephonic survey, and a Healthy Group comprising 25 healthy individuals matched for sex and age by face-to-face interview. The Stanford HAQ 20-Item Disability Scale (HAQ) and the Short Form Health Survey (SF-12) questionnaires were administered to both groups. Generalized Linear Models, Pearson χ2 tests, and odds ratios were used to evaluate the test results.

Results: Significant differences in functional capacity and quality of life were observed between the Chikungunya and Healthy Groups. The chance of some impairment in functionality was also much higher in the Chikungunya Group in four of the HAQ categories, especially in the "walking" category (adjusted OR= 109.40). Further, the Chikungunya Group had a higher chance of presenting a below-average score in the mental component summary of the SF-12 (adjusted OR= 16.20) and of being positive in depression risk screening (adjusted OR= 34.57).

Conclusion: Even one year after the acute phase, chikungunya fever can compromise the functionality and quality of life in affected individuals, with direct impairment in performing daily activities. Studies and therapeutic plans for chikungunya fever should consider the long-term impacts of this disease.

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Conflict of interest statement

Conflict of interest: none.

Figures

None
Graphical abstract
Figure 1
Figure 1. Flowchart showing the recruitment and selection of the Chikungunya Fever Group participants
See this image and copyright information in PMC

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