[Cerebromeningeal amyloid angiopathy]

Abstract

Amyloid angiopathy represents 20% of causes of intraparenchymal hematoma. The histopathological examination must carefully look for characteristic vascular abnormalities and the immunohistochemistry for the βA4 peptide must be carried out systematically. In practice, the evacuation products of an intracerebral hematoma must be fully included, because the lesions may be focal. The existence of a neurosurgical history may suggest an iatrogenic etiology when patients are less than 55 years-old.

Keywords: Amyloid angiopathy; Angiopathie amyloïde; Peptide βA4; βA4 peptide.