Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Nov;21(11):747-750.
doi: 10.1038/s41575-024-00990-5. Epub 2024 Oct 2.

MASLD: a disease in flux

Affiliations

MASLD: a disease in flux

Alina M Allen et al. Nat Rev Gastroenterol Hepatol. 2024 Nov.
No abstract available

PubMed Disclaimer

References

    1. Loomba, R., Friedman, S. L. & Shulman, G. I. Mechanisms and disease consequences of nonalcoholic fatty liver disease. Cell 184, 2537–2564 (2021). - DOI - PubMed
    1. Fabbrini, E. et al. Phase 1 trials of PNPLA3 siRNA in I148M homozygous patients with MAFLD. N. Engl. J. Med. 391, 475–476 (2024). - DOI - PubMed
    1. Maeso-Díaz, R. et al. Targeting senescent hepatocytes using the thrombomodulin-PAR1 inhibitor vorapaxar ameliorates NAFLD progression. Hepatology 78, 1209–1222 (2023). - DOI - PubMed
    1. Yashaswini, C. N. et al. Phenotypes and ontogeny of senescent hepatic stellate cells in metabolic dysfunction-associated steatohepatitis. J. Hepatol. 81, 207–217 (2024). - DOI - PubMed
    1. Arab, J. P., Arrese, M. & Trauner, M. Recent insights into the pathogenesis of nonalcoholic fatty liver disease. Annu. Rev. Pathol. 13, 321–350 (2018). - DOI - PubMed

LinkOut - more resources