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. 2024 May 20;15(5):879-881.
doi: 10.4103/idoj.idoj_663_23. eCollection 2024 Sep-Oct.

Levothyroxine-Induced Systemic Lupus Erythematosus in a Patient with Hypothyroidism: A Rare Case Report

Angoori G Rao  1 , M Naresh  1 , Praveen Kumar  1 , Anmisha Bandaru  1
Affiliations

Levothyroxine-Induced Systemic Lupus Erythematosus in a Patient with Hypothyroidism: A Rare Case Report

Angoori G Rao et al. Indian Dermatol Online J. .
No abstract available

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Erythematous patch over the left malar region, nose, and multiple atrophic macules over the right malar region with perioral pigmentation
Figure 2
Figure 2
Lamellar orthokeratosis, follicular plugging, flattening of rete ridges, prominent basal cell vacuolar degeneration, and thickened basement membrane in the epidermis. The dermis showed edema with perivascular and periappendageal lymphocytic infiltrate (H and E, 10x)
Figure 3
Figure 3
Direct immunofluorescence study showing granular IgG deposits along the basement membrane (10x)
See this image and copyright information in PMC

References

    1. Bataille P, Lebrun-Vignes B, Tubach F, Aroux-Pavard M, Philibert C, Chasset F, et al. Proton pump inhibitors associated with drug induced lupus erythematosus. JAMA Dermatol. 2022;158:1208–10. - PMC - PubMed
    1. Haugaard JH, Kofoed K, Gislason G, Dreyer L, Egeberg A. “Association between drug use and subsequent diagnosis of lupus erythematosus.”. JAMA Dermatol. 2020;156:1199–207. - PMC - PubMed

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