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Case Reports
. 2024 Sep 4;29(17):102488.
doi: 10.1016/j.jaccas.2024.102488.

Coronary Artery Aneurysm Thrombosis Causing Acute Myocardial Infarction in an Adolescent With Neurofibromatosis Type 1

Filippo Russo  1 , Alessandro Beneduce  1 , Barbara Parma  2 , Angelo Selicorni  2 , Carlo Campana  3 , Cecilia Marcolin  4 , Raffaella Picchi  2 , Alaide Chieffo  1   4 , Matteo Montorfano  1   4
Affiliations
Case Reports

Coronary Artery Aneurysm Thrombosis Causing Acute Myocardial Infarction in an Adolescent With Neurofibromatosis Type 1

Filippo Russo et al. JACC Case Rep. .

Abstract

Acute myocardial infarction is a rare though possible occurrence in young patients, especially with predisposing conditions, and the treatment is still debated. We present the case of a teenager known to have neurofibromatosis type 1 with acute coronary syndrome caused by coronary aneurysms and thrombotic occlusion of the left circumflex artery treated with a stent-sparing strategy.

Keywords: coronary artery aneurysm; myocardial infarction; neurofibromatosis; pediatric cardiology.

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Conflict of interest statement

The authors have reported that they have no relationships relevant to the contents of this paper to disclose.

Figures

None
Graphical abstract
Figure 1
Figure 1
Clinical Presentation and Baseline Coronary Angiography At hospital admission, electrocardiogram shows posterior myocardial infarction. Coronary angiography demonstrates acute thrombotic occlusion of a giant aneurysm of the proximal LCX (arrow) and a further giant aneurysm of the proximal right coronary artery.
Figure 2
Figure 2
Conservative Management of Coronary Artery Aneurysm Thrombosis Thrombectomy using manual thrombus aspiration catheter (box) with removal of thrombus is shown. Post-thrombectomy angiogram demonstrates flow restoration and residual thrombotic burden (asterisks) in the LCX.
Figure 3
Figure 3
Follow-Up Coronary Angiography Follow-up angiography after 7 days of antithrombotic therapy showing complete thrombus resolution in the LCX.
See this image and copyright information in PMC

References

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