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Meta-Analysis
. 2024 Oct;16(10):e13610.
doi: 10.1111/1753-0407.13610.

Prevalence and influencing factors of malnutrition in diabetic patients: A systematic review and meta-analysis

Tong Zhang  1 , Jiangxia Qin  1 , Jiali Guo  1 , Jianhui Dong  1 , Junbo Chen  1 , Yuxia Ma  1 , Lin Han  1   2
Affiliations
Meta-Analysis

Prevalence and influencing factors of malnutrition in diabetic patients: A systematic review and meta-analysis

Tong Zhang et al. J Diabetes. 2024 Oct.

Abstract

The prevalence of malnutrition in diabetic patients and its influencing factors remain poorly described. We aim to investigate the prevalence of malnutrition and the influencing factors in diabetic patients through meta-analysis. Utilizing search terms, such as diabetes, malnutrition, and prevalence, we systematically searched eight databases, including Embase, PubMed, Web of Science, The Cochrane Library, China Knowledge Resource Integrated Database (CNKI), Wanfang Database, Chinese Biomedical Database (CBM), and VIP Database, from inception to May 4, 2023. The search aimed to identify studies related to the prevalence of malnutrition and its influencing factors in adult patients with diabetes. Cohort studies, case-control studies, and cross-sectional studies that met the inclusion criteria were included in the analysis. Stata 16.0 software was used for meta-analysis. Quality of the evidence was assessed using Grading of Recommendations, Assessment, Development and Evaluation (GRADE). The study protocol is registered with Prospective Register of Systematic Reviews (PROSPERO), CRD42023443649. A total of 46 studies were included, involving 18 062 patients with ages ranging from 18 to 95 years. The overall malnutrition prevalence was 33% (95% confidence interval [CI]: 0.25-0.40), compared with an at-risk prevalence of 44% (95% CI: 0.34-0.54). Sixteen factors associated with malnutrition in diabetic patients were identified. This meta-analysis provides insights into the prevalence of malnutrition and its risk factors in diabetic patients. Regular nutritional screening for patients with risk factors is essential for early detection and intervention.

Keywords: diabetes; influencing factors; malnutrition; meta‐analysis; prevalence.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

FIGURE 1
FIGURE 1
The flow chart of studies selecting process. CBM, Chinese Biomedical Database; CNKI, China Knowledge Resource Integrated Database.
FIGURE 2
FIGURE 2
The forest plot of prevalence of malnutrition in diabetic patients. CI, confidence interval; ES, effect size.
FIGURE 3
FIGURE 3
The forest plot of the prevalence of at‐risk for malnutrition in diabetic patients. CI, confidence interval; ES, effect size.
FIGURE 4
FIGURE 4
Funnel plot for assessing publication biases. MD, mean difference.
See this image and copyright information in PMC

References

    1. Zimmet P, Alberti KG, Shaw J. Global and societal implications of the diabetes epidemic. Nature. 2001;414:782‐787. doi:10.1038/414782a - DOI - PubMed
    1. Fowler MJ. Microvascular and macrovascular complications of diabetes. Clin Diabetes. 2008;26:77‐82. doi:10.2337/diaclin.26.2.77 - DOI
    1. Liu GX, Chen Y, Yang YX, et al. Pilot study of the Mini Nutritional Assessment on predicting outcomes in older adults with type 2 diabetes. Geriatr Gerontol Int. 2017;17:2485‐2492. doi:10.1111/ggi.13110 - DOI - PubMed
    1. López‐Valverde ME, Aragón‐Sánchez J, Víquez‐Molina G. Handgrip strength but not malnutrition according to global leadership initiative on malnutrition criteria is a risk factor for mortality in hospitalized patients with ischemic diabetic foot ulcers. Adv Wound Care. 2023;12:127‐134. doi:10.1089/wound.2021.0109 - DOI - PubMed
    1. Schuetz P, Seres D, Lobo DN, Gomes F, Kaegi‐Braun N, Stanga Z. Management of disease‐related malnutrition for patients being treated in hospital. Lancet. 2021;398:1927‐1938. doi:10.1016/s0140-6736(21)01451-3 - DOI - PubMed

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