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. 2024 Oct;35(10):e14253.
doi: 10.1111/pai.14253.

Airway bacterial colonization is associated with bronchial remodeling in severe preschool wheezers

Fabien Beaufils  1   2   3 , Laurence Delhaes  1   2   3 , Pauline Esteves  1   3 , Marine Michelet  4   5 , Cécile Bébéar  6 , Hugues Begueret  2 , Michael Fayon  1   2   3 , Patrick Berger  1   2   3
Affiliations

Airway bacterial colonization is associated with bronchial remodeling in severe preschool wheezers

Fabien Beaufils et al. Pediatr Allergy Immunol. 2024 Oct.
No abstract available

Keywords: asthma; bronchial biopsies; broncho‐alveolar lavage; epithelium; inflammation; smooth muscle; virus.

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References

REFERENCES

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    1. Saglani S. Preventing progression of preschool wheezing to asthma: opportunities for intervention. Pediatr Allergy Immunol. 2024;35:e14180.
    1. Bisgaard H, Hermansen MN, Buchvald F, et al. Childhood asthma after bacterial colonization of the airway in neonates. N Engl J Med. 2007;357:1487‐1495.
    1. Crisford H, Sapey E, Rogers GB, et al. Neutrophils in asthma: the good, the bad and the bacteria. Thorax. 2021;76:835‐844.
    1. Beaufils F, Mondenx M, Fayon M, et al. Bronchial remodeling identifies new endotypes in severe preschool wheezers. Am J Respir Crit Care Med. 2024;210:941‐944.