Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2024 Sep 4;16(9):e68604.
doi: 10.7759/cureus.68604. eCollection 2024 Sep.

An 8-Year-Old Boy With Hepatic Embryonal Sarcoma Managed With Surgical Resection

Affiliations
Case Reports

An 8-Year-Old Boy With Hepatic Embryonal Sarcoma Managed With Surgical Resection

Ali K Alshaya et al. Cureus. .

Abstract

The extent of hepatic tumors in childhood differs from that found in older age groups. Some of these tumors are believed to be quite rare like undifferentiated embryonal sarcoma of the liver (UESL). The challenge in diagnosis arises from the nonspecific clinical, biochemical, and radiological features, with definitive diagnosis requiring pathological confirmation following surgical excision. Treatment options with neoadjuvant chemotherapy and surgical resection with satisfactory outcomes have been reported in the literature as well as in our case. We present the case of an 8-year-old boy who initially presented with nonspecific symptoms and was diagnosed with UESL. Following a multidisciplinary team discussion, he was treated with chemotherapy and surgical resection. Post-resection follow-up with MRI revealed stable findings.

Keywords: abdominal mass; embryonal; hepatic; malignancy; sarcoma.

PubMed Disclaimer

Conflict of interest statement

Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

Figures

Figure 1
Figure 1. CT abdomen with IV contrast showing hypervascular lesion in the right lobe measuring 15.8 × 12.8 × 16 cm
A: Axial view; B: Coronal view
Figure 2
Figure 2. Coronal view of MRI abdomen showing well-defined encapsulated mass of mixed signal intensities measuring approximately 17.6 × 14.3 × 15 cm
Figure 3
Figure 3. CT abdomen with IV contrast showing significant interval decrease in the size of the right hepatic lobe mass to 11.4 × 10.8 × 12.6 cm
A: Axial view; B: Coronal view

References

    1. Hepatic tumours in childhood: An experience at the Children Hospital and Institute of Child Health, Lahore. Zaman S, Hanif G, Hussain M, et al. https://pubmed.ncbi.nlm.nih.gov/22125982/ J Pak Med Assoc. 2011;61:1079–1082. - PubMed
    1. Undifferentiated embryonal sarcoma of the liver (UESL): A single-center experience and review of the literature. Techavichit P, Masand PM, Himes RW, et al. J Pediatr Hematol Oncol. 2016;38:261–268. - PubMed
    1. Undifferentiated embryonal sarcoma of the liver: Clinical characteristics and outcomes. Zhang C, Jia CJ, Xu C, Sheng QJ, Dou XG, Ding Y. World J Clin Cases. 2020;8:4763–4772. - PMC - PubMed
    1. Undifferentiated (embryonal) liver sarcoma: Reviaew of 6 cases in National Cancer Institute, Lima, Peru. Review of the literature. (Article in Spanish) Dueñas D, Huanca L, Cordero M, Webb P, Ruiz E. https://pubmed.ncbi.nlm.nih.gov/27131944/ Rev Gastroenterol Peru. 2016;36:71–76. - PubMed
    1. Undifferentiated embryonal liver sarcoma: case report and review of the literature. (Article in Spanish) Pérez-Rodríguez VM, Muñiz-Ronquillo T, Ponce-Camacho MA, Rodríguez-Garza CY. Bol Med Hosp Infant Mex. 2021;78:647–651. - PubMed

Publication types

LinkOut - more resources