Rhabdomyolysis and Pigment Nephropathy - An Uncommon Manifestation of Eucalyptus Oil Consumption

Abstract

Eucalyptus oil consumption is well known to cause adverse effects on central nervous system like seizures, ataxia and unconsciousness. No antidote is available and treatment is largely supportive. We report a case of rhabdomyolysis with pigment cast nephropathy and acute kidney injury in a young female following eucalyptus oil consumption and its successful management.

Keywords: AKI; Cast nephropathy; Eucalyptus Oil; Rhabdomyolysis.

Figure 1:

Light microscopic and immunofluorescence findings of kidney biopsy. (a) 20x, PAS: Renal cortex showing normal glomerulus. Few tubules contain atypical globular casts with associated acute tubular injury. (b) 40x, H and E: Tubules containing atypical red globular casts with attenuation of the proximal tubular epithelial cells, cytoplasmic vacuolization, and variable loss of the brush borders. (c) 20x: The atypical intratubular casts and some of the tubular epithelial cells stain positively for myoglobin immunohistochemistry. (d) 20x, H and E: Mild edema and interstitial inflammation.