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Case Reports
. 2024 Sep 2:49:2.
doi: 10.11604/pamj.2024.49.2.44247. eCollection 2024.

Acute severe hepatitis and COVID-19: case report

Saber Hmimass  1 , Maryeme Kadiri  1 , Mohamed Borahma  1 , Fatima-Zahra Chabib  1 , Camelia Berhili  1 , Nawa Lagdali  1 , Imane Ben Elbarhdadi  1 , Fatima-Zahra Ajana  1
Affiliations
Case Reports

Acute severe hepatitis and COVID-19: case report

Saber Hmimass et al. Pan Afr Med J. .

Abstract

COVID-19, caused by SARS-CoV-2, has been declared an international public health emergency. Patients with COVID-19, even without a history of liver disease, frequently present with liver test disturbances. Due to the multisystemic involvement of COVID-19, the pathogenesis of liver injury is likely to be multifactorial, involving systemic inflammation, small vessel thrombosis, hepatic hypoxia, and potential drug toxicity, ruling out direct infection of hepatocytes by SARS-CoV-2. COVID-19 can cause severe acute hepatitis. We report the case of a 25-year-old man admitted to emergency with abdominal pain who presented with acute severe liver failure before respiratory signs.

Keywords: COVID-19; case report; severe acute hepatitis.

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Conflict of interest statement

The authors declare no competing interests.

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