Mex3a Protects Against Atherosclerosis: Evidence From Mice and Humans

Donato Santovito^#^{1

2

3}, James M Henderson^#^{1

2}, Kiril Bidzhekov^#¹, Vasiliki Triantafyllidou¹, Yvonne Jansen¹, Zhifen Chen^{2

4}, Floriana M Farina^{1

2}, Anastasiia Diagel⁴, Maria Aslani¹, Xavier Blanchet¹, Heribert Schunkert^{2

4}, Remco T A Megens^{1

2

5}, Yvonne Döring^{1

2

6}, Michael Sattler^{7

8}, Christian Weber^{1

2

9

10

11}

Affiliations

¹ Institute for Cardiovascular Prevention, Ludwig-Maximilians-Universität, Munich, Germany (D.S., J.M.H., K.B., V.T., Y.J., F.M.F., M.A., X.B., R.T.A.M., Y.D., C.W.).
² German Centre for Cardiovascular Research, partner site Munich Heart Alliance, Germany (D.S., J.M.H., Z.C., F.M.F., H.S., R.T.A.M., Y.D., C.W.).
³ Institute for Genetic and Biomedical Research, Unit of Milan, National Research Council, Italy (D.S.).
⁴ Department of Cardiology, Deutsches Herzzentrum München (Z.C., A.D., H.S.), Technical University of Munich, Germany.
⁵ Departments of Biomedical Engineering (R.T.A.M.), Cardiovascular Research Institute Maastricht, Maastricht University, the Netherlands.
⁶ Division of Angiology, Swiss Cardiovascular Center, Inselspital, University Hospital of Bern, Switzerland (Y.D.).
⁷ Center for Integrated Protein Science Munich at Biomolecular NMR Spectroscopy, Department of Chemistry (M.S.), Technical University of Munich, Germany.
⁸ Institute of Structural Biology, Helmholtz Zentrum München, Neuherberg, Germany (M.S.).
⁹ Biochemistry (C.W.), Cardiovascular Research Institute Maastricht, Maastricht University, the Netherlands.
¹⁰ Cluster for Nucleic Acid Therapeutics Munich, Germany (C.W.).
¹¹ Munich Cluster for Systems Neurology, Germany (C.W.).

^# Contributed equally.

Donato Santovito et al. Circulation. 2024.

. 2024 Oct 8;150(15):1213-1216.

doi: 10.1161/CIRCULATIONAHA.124.069526. Epub 2024 Oct 7.

¹ Institute for Cardiovascular Prevention, Ludwig-Maximilians-Universität, Munich, Germany (D.S., J.M.H., K.B., V.T., Y.J., F.M.F., M.A., X.B., R.T.A.M., Y.D., C.W.).
² German Centre for Cardiovascular Research, partner site Munich Heart Alliance, Germany (D.S., J.M.H., Z.C., F.M.F., H.S., R.T.A.M., Y.D., C.W.).
³ Institute for Genetic and Biomedical Research, Unit of Milan, National Research Council, Italy (D.S.).
⁴ Department of Cardiology, Deutsches Herzzentrum München (Z.C., A.D., H.S.), Technical University of Munich, Germany.
⁵ Departments of Biomedical Engineering (R.T.A.M.), Cardiovascular Research Institute Maastricht, Maastricht University, the Netherlands.
⁶ Division of Angiology, Swiss Cardiovascular Center, Inselspital, University Hospital of Bern, Switzerland (Y.D.).
⁷ Center for Integrated Protein Science Munich at Biomolecular NMR Spectroscopy, Department of Chemistry (M.S.), Technical University of Munich, Germany.
⁸ Institute of Structural Biology, Helmholtz Zentrum München, Neuherberg, Germany (M.S.).
⁹ Biochemistry (C.W.), Cardiovascular Research Institute Maastricht, Maastricht University, the Netherlands.
¹⁰ Cluster for Nucleic Acid Therapeutics Munich, Germany (C.W.).
¹¹ Munich Cluster for Systems Neurology, Germany (C.W.).

^# Contributed equally.

No abstract available

Keywords: RNA-binding proteins; atherosclerosis; coronary artery disease; genetics.

Conflict of interest statement

None.