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. 2024 Oct 7;15(1):8662.
doi: 10.1038/s41467-024-53126-3.

Strengthening and expanding capacities in clinical trials: advancing pandemic prevention, preparedness and response in Africa

Nicaise Ndembi  1 , Tadesse T Mekonen  2 , Morenike Oluwatoyin Folayan  3 , Nebiyu Dereje  4 , Adriaan Kruger  5 , Joseph Fokam  6 , Elvis Temfack  4 , Tajudeen Raji  4 , Jean Nachega  7 , Yap Boum 2nd  8 , Trevor A Crowell  9 , Alain Ngashi Ngongo  4 , Souleymane Mboup  10 , Francine Ntoumi  11 , Glaudina Loots  12 , Michael Makanga  13 , Samba Sow  14 , Salim Abdool Karim  15 , John Nkengasong  16
Affiliations

Strengthening and expanding capacities in clinical trials: advancing pandemic prevention, preparedness and response in Africa

Nicaise Ndembi et al. Nat Commun. .

Abstract

Enhancing the clinical trial capabilities within Africa is essential to augment the continent’s pandemic prevention, preparedness and response efforts. Here, we describe the critical challenges of clinical trials in Africa and draw upon the lessons learnt from the Consortium for COVID-19 Vaccine Clinical Trials (CONCVACT) experience, such as the importance of regional collaboration, capacity building and establishing standardized protocols.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1. Distribution of CONCNVACT network research centers across Africa.
This map provides a visual representation of the geographical distribution of the 21 research centers affiliated with the CONCVACT Network across Africa. Black pins: Indicate the locations of individual research centers. Green pin: Marks the location of the CONCVACT Network itself.
Fig. 2
Fig. 2
R&D Centers will regionally consolidate infrastructure, capacity and expertise across a given portion of the R&D value chain supported by a Coordinating Platform.
See this image and copyright information in PMC

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