Comprehensive endometriosis care: a modern multimodal approach for the treatment of pelvic pain and endometriosis
- PMID: 39376635
- PMCID: PMC11457249
- DOI: 10.1177/26334941241277759
Comprehensive endometriosis care: a modern multimodal approach for the treatment of pelvic pain and endometriosis
Abstract
Endometriosis is a prevalent gynecological disease, leading to chronic pain and inflammation, affecting 1 in 10 individuals presumed female at birth. The diagnostic journey is often arduous, marked by neglect of the right diagnosis and prolonged wait times, significantly compromising the quality of life among those affected. This review provides a nuanced exploration of endometriosis-associated pain management, encompassing medical, surgical, and holistic approaches, all guided by accurate and refined diagnostics. Our paramount goal is to empower physicians as key figures in confronting this intricate challenge with a patient-centric approach, ultimately aiming to improve treatment and quality of life. Acknowledging each patient's unique needs, we emphasize the importance of tailoring a spectrum of options informed by current literature and insights gleaned from our experience in a high-volume tertiary endometriosis center. It is imperative to recognize endometriosis as a complex and chronic disease, often occurring with co-morbid conditions and nuanced complexities, necessitating a long-term personalized multimodal approach for each case. In addition, incorporating principles such as patient autonomy, profound respect for diverse experiences, and practical education on treatment choices is pivotal in enhancing treatment outcomes and overall patient satisfaction.
Keywords: endometriosis; management; pain; treatments.
Plain language summary
Navigating the landscape of endometriosis: a comprehensive approach to pain management and patient-centered care Endometriosis is a common gynecological condition characterized by persistent pelvic pain and inflammation, impacting approximately one in ten individuals assigned female at birth. Diagnosis often entails a challenging journey, with many experiencing delays in obtaining the correct diagnosis and treatment due to various factors, significantly affecting their quality of life. This review delves into the intricate landscape of managing pain associated with endometriosis, encompassing medical interventions, surgical procedures, and holistic therapies. Our primary aim is to equip healthcare providers with the tools and knowledge necessary to effectively address this complex issue, prioritizing patient-centered care to minimize delays in diagnosis and treatment initiation. Recognizing the individuality of each patient’s needs, we advocate for a tailored approach informed by current evidence and clinical experience from specialized endometriosis centers. Furthermore, we underscore the importance of patient autonomy, respecting diverse perspectives, and providing comprehensive education on treatment options to optimize treatment outcomes and patient satisfaction.
© The Author(s), 2024.
Conflict of interest statement
S.F. reports advocacy work with the Endometriosis Network Canada and EndoACT, outside the submitted work. M.L. reports grants from Australian MRFF, AbbVie, CanSAGE, Hamilton Health Sciences, Hyivy, Pfizer; honoraria for lectures/writing from AIUM, GE Healthcare, Bayer, AbbVie, TerSera; consultancy work with AbbVie, Hologic, Chugai, Roche Diagnostics, AIMA, Pfizer, affiliations with Imagendo, outside the submitted work.
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References
-
- Zondervan KT, Becker CM, Missmer SA. Endometriosis. N Engl J Med 2020; 382(13): 1244–1256. - PubMed
-
- Australian Institute of Health and Welfare. Endometriosis, https://www.aihw.gov.au/reports/chronic-disease/endometriosis-in-austral... (2023, accessed 11 Decemeber 2023).
-
- Johnson NP, Hummelshoj L, Adamson GD, et al.. World endometriosis society consensus on the classification of endometriosis. Hum Reprod 2017; 32(2): 315–324. - PubMed
-
- Agarwal SK, Chapron C, Giudice LC, et al.. Clinical diagnosis of endometriosis: a call to action. Am J Obstet Gynecol 2019; 220(4): 354.e1–354.e12. - PubMed
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