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. 2024 Sep 23:15:1460073.
doi: 10.3389/fneur.2024.1460073. eCollection 2024.

A case of spontaneous bilateral epidural hematoma associated with decreased coagulation factor XII activity: case report and literature review

Zhuxiao Tang  1 , Ming Wang  1 , Tao Xiong  1 , Weixian Liu  1 , Hu Sun  1 , Jiangchun Ma  1
Affiliations

A case of spontaneous bilateral epidural hematoma associated with decreased coagulation factor XII activity: case report and literature review

Zhuxiao Tang et al. Front Neurol. .

Abstract

Epidural hematoma typically manifests following craniocerebral trauma, stemming from injury to the meningeal artery or venous system, predominantly on one side. Instances of spontaneous epidural hematoma are uncommon, with occurrences of spontaneous bilateral epidural hematoma being exceedingly rare. Sickle cell disease, adjacent paranasal sinusitis, and tumor metastases are the most prevalent causes of spontaneous epidural hematoma. This case study presents an individual with abdominal liposarcoma exhibiting reduced coagulation factor XII activity, who experienced sudden unconsciousness due to spontaneous acute bilateral epidural hematoma, and subsequently achieved a favorable outcome following surgical intervention.

Keywords: coagulation factor XII; epidural hematoma; intracranial; non-traumatic; spontaneous.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Preoperative intracranial epidural hematoma is shown from different sections: (A) cross-section, (B) sagittal section.
Figure 2
Figure 2
Intraoperatively, after opening the bilateral frontal bone flaps adjacent to the sagittal sinus, a large amount of epidural hematoma is observed.
Figure 3
Figure 3
Postoperatively, a cranial CT scan was performed: (A) cross-section, (B) sagittal section.
See this image and copyright information in PMC

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