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Editorial
. 2024 Oct 15;13(20):e038202.
doi: 10.1161/JAHA.124.038202. Epub 2024 Oct 8.

Calcium Channels, Clustering, and Single-Amino Acid Control of Blood Pressure and Blood Flow

Affiliations
Editorial

Calcium Channels, Clustering, and Single-Amino Acid Control of Blood Pressure and Blood Flow

Lars Jørn Jensen. J Am Heart Assoc. .
No abstract available

Keywords: CaV1.2; Editorials; L‐type channels; amino acid phosphorylation; blood flow regulation; hypertension; ion channel clustering.

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Comment on

  • α1C S1928 Phosphorylation of CaV1.2 Channel Controls Vascular Reactivity and Blood Pressure.
    Flores-Tamez VA, Martín-Aragón Baudel M, Hong J, Taylor JL, Ren L, Le T, Syed AU, Moustafa Y, Singhrao N, Lemus-Martinez WR, Reddy GR, Ramer V, Man KNM, Bartels P, Chen-Izu Y, Chen CY, Simo S, Dickson EJ, Morotti S, Grandi E, Santana LF, Hell JW, Horne MC, Nieves-Cintrón M, Navedo MF. Flores-Tamez VA, et al. J Am Heart Assoc. 2024 Oct 15;13(20):e035375. doi: 10.1161/JAHA.124.035375. Epub 2024 Oct 8. J Am Heart Assoc. 2024. PMID: 39377203 Free PMC article.

References

    1. Flores‐Tamez VA, Baudel MMA, Hong J, Taylor JL, Ren L, Le T, Syed AU, Moustafa Y, Singhrao N, Lemus‐Martinez WR, et al. α1C S1928 phosphorylation of CaV1.2 channel controls vascular reactivity and blood pressure. J Am Heart Assoc. 2024;13:e035375. doi: 10.1161/JAHA.124.035375 - DOI - PMC - PubMed
    1. Catterall WA, Perez‐Reyes E, Snutch TP, Striessnig J. International Union of Pharmacology. XLVIII. Nomenclature and structure‐function relationships of voltage‐gated calcium channels. Pharmacol Rev. 2005;57:411–425. doi: 10.1124/pr.57.4.5 - DOI - PubMed
    1. Hofmann F, Flockerzi V, Kahl S, Wegener JW. L‐type CaV1.2 calcium channels: from in vitro findings to in vivo function. Physiol Rev. 2014;94:303–326. doi: 10.1152/physrev.00016.2013 - DOI - PubMed
    1. Liao P, Yu D, Li G, Yong TF, Soon JL, Chua YL, Soong TW. A smooth muscle Cav1.2 calcium channel splice variant underlies hyperpolarized window current and enhanced state‐dependent inhibition by nifedipine. J Biol Chem. 2007;282:35133–35142. doi: 10.1074/jbc.M705478200 - DOI - PubMed
    1. Nystoriak MA, Murakami K, Penar PL, Wellman GC. Ca(v)1.2 splice variant with exon 9* is critical for regulation of cerebral artery diameter. Am J Physiol Heart Circ Physiol. 2009;297:H1820–H1828. doi: 10.1152/ajpheart.00326.2009 - DOI - PMC - PubMed

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