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Randomized Controlled Trial
. 2024 Oct 1;7(10):e2438453.
doi: 10.1001/jamanetworkopen.2024.38453.

Mindfulness Meditation vs Escitalopram for Treatment of Anxiety Disorders: Secondary Analysis of a Randomized Clinical Trial

Hiroe Hu  1 , Mihriye Mete  2 , Neil K Rustgi  3 , Charisma I Washington  3 , Kavya Sanghavi  2 , Mary Ann Dutton  3 , Naomi M Simon  4 , Amanda W Baker  5 , Eric Bui  6 , Elizabeth A Hoge  3
Affiliations
Randomized Controlled Trial

Mindfulness Meditation vs Escitalopram for Treatment of Anxiety Disorders: Secondary Analysis of a Randomized Clinical Trial

Hiroe Hu et al. JAMA Netw Open. .
No abstract available

Plain language summary

This secondary analysis of a randomized clinical trial assesses patient-reported anxiety, depression, and quality of life among patients receiving mindfulness-based stress reduction vs escitalopram for the treatment of anxiety disorders.

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Conflict of interest statement

Conflict of Interest Disclosures: In the past 3 years, Dr Simon reported receiving grants from the National Institutes of Health (NIH), American Foundation for Suicide Prevention, Patient-Centered Outcomes Research Institute (PCORI), Ananda Scientific and support from Cohen Veterans Network and MindMed; receiving personal fees from Genomind, Cerevel; receiving fees or royalties from Wiley (Deputy Editor Depression and Anxiety), Wolters Kluwer (UpToDate), and APA Publishing; and having spousal stock from G1 Therapeutics and Zentalis outside the submitted work. Dr Bui reported receiving grants from PCORI and a private donor during the conduct of the study. In addition, Dr Bui reported receiving grants from Réseau d’Intérêt Normandie and the University Hospital Center of Caen, receiving royalties from Springer and Wolters Kluwer Health, and receiving consulting fees from Cerevel Therapeutics outside the submitted work. Dr Hoge reported receiving grants from PCORI during the conduct of the study. No other disclosures were reported.

References

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    1. Hoge EA, Bui E, Mete M, Dutton MA, Baker AW, Simon NM. Mindfulness-based stress reduction vs escitalopram for the treatment of adults with anxiety disorders: a randomized clinical trial. JAMA Psychiatry. 2023;80(1):13-21. doi:10.1001/jamapsychiatry.2022.3679 - DOI - PMC - PubMed
    1. Hoge EA, Bui E, Mete M, et al. . Treatment for Anxiety: Mindfulness Meditation Versus Escitalopram (TAME): design of a randomized, controlled non-inferiority trial. Contemp Clin Trials. 2020;91:105965. doi:10.1016/j.cct.2020.105965 - DOI - PubMed
    1. Ebrahiminejad S, Poursharifi H, Bakhshiour Roodsari A, Zeinodini Z, Noorbakhsh S. The effectiveness of mindfulness-based cognitive therapy on Iranian female adolescents suffering from social anxiety. Iran Red Crescent Med J. 2016;18(11):e25116. doi:10.5812/ircmj.25116 - DOI - PMC - PubMed

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