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Multicenter Study
. 2024 Dec 1;119(12):2532-2539.
doi: 10.14309/ajg.0000000000003035. Epub 2024 Sep 4.

Risk Factors for Serrated Polyps: Results From a Large, Multicenter Colonoscopy-Based Study

Seth D Crockett  1 , Aasma Shaukat  2 , Olivia Delau  2 , Elena M Stoffel  3 , Timothy R Church  4 , Sapna Syngal  5 , Robert Bresalier  6
Affiliations
Multicenter Study

Risk Factors for Serrated Polyps: Results From a Large, Multicenter Colonoscopy-Based Study

Seth D Crockett et al. Am J Gastroenterol. .

Abstract

Introduction: Risk factors for serrated polyps (SPs) are not well understood.

Methods: Multivariable analyses of data from a multicenter colonoscopy-based study estimated odds ratios for having either a sessile serrated lesion or traditional serrated adenoma according to participant characteristics.

Results: Six thousand seventy-eighty participants were included in the analyses (565 with either a sessile serrated lesion or traditional serrated adenoma). White race was associated with a higher risk of SPs compared with Black race (adjusted odds ratio 4.64, 95% confidence interval 1.89-11.41). Obesity and current smoking were also associated with a higher risk of SPs.

Discussion: White race, smoking, and obesity are risk factors for precancerous SPs.

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Conflict of interest statement

CONFLICTS OF INTEREST

Guarantor of the article: Seth D. Crockett, MD, MPH.

References

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