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. 2024 Oct 4:119:e240093.
doi: 10.1590/0074-02760240093. eCollection 2024.

Advances in the development of new vaccines for tuberculosis and Brazil's role in the effort forward the end TB strategy

Ana Paula Junqueira-Kipnis  1   2 , Luciana Cesar de Cerqueira Leite  3   2 , Júlio Croda  4   5   6   2 , Erica Chimara  7   2 , Anna Cristina C Carvalho  8   2 , Ricardo Alexandre Arcêncio  9   2
Affiliations

Advances in the development of new vaccines for tuberculosis and Brazil's role in the effort forward the end TB strategy

Ana Paula Junqueira-Kipnis et al. Mem Inst Oswaldo Cruz. .

Abstract

Tuberculosis (TB) continues to be the world's leading killer of infectious diseases. Despite global efforts to gradually reduce the number of annual deaths and the incidence of this disease, the coronavirus disease 19 (COVID-19) pandemic caused decreased in TB detection and affected the prompt treatment TB which led to a setback to the 2019 rates. However, the development and testing of new TB vaccines has not stopped and now presents the possibility of implanting in the next five years a new vaccine that is affordable and might be used in the various key vulnerable populations affected by TB. Then, this assay aimed to discuss the main vaccines developed against TB that shortly could be selected and used worldwide, and additionally, evidence the Brazilian potential candidates' vaccines in developing in Brazil that could be considered among those in level advanced to TB end.

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Conflict of interest statement

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. The authors have no conflict of interest to declare.

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