Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1985;2(4):230-4.
doi: 10.1159/000467866.

Human plasma fibronectin effect on serum-mediated uptake of Pseudomonas aeruginosa PA 1348A by human granulocytes

M J Boulanger, R P Smith, A L Baltch, F A Blumenstock, T M Saba

Human plasma fibronectin effect on serum-mediated uptake of Pseudomonas aeruginosa PA 1348A by human granulocytes

M J Boulanger et al. Complement. 1985.

Abstract

The effect of human plasma fibronectin on human granulocyte (PMN) phagocytosis of one strain of Pseudomonas aeruginosa (PA 1348A) was examined in a previously defined optimal phagocytic assay. Normal and fibronectin-deficient serum demonstrated similar rates of bacterial uptake by PMNs. Complement depletion of both sera inhibited phagocytosis. Addition of purified fibronectin did not alter phagocytosis. These findings strongly support the conclusion that fibronectin neither promotes nor inhibits opsonization for phagocytosis of this strain of P. aeruginosa.

PubMed Disclaimer

Publication types