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Review
. 2024 Oct 15;5(10):101786.
doi: 10.1016/j.xcrm.2024.101786. Epub 2024 Oct 8.

Clinical pain management: Current practice and recent innovations in research

Jing Wang  1 , Lisa V Doan  2
Affiliations
Review

Clinical pain management: Current practice and recent innovations in research

Jing Wang et al. Cell Rep Med. .

Abstract

Chronic pain affects one in five adults. It is not only a major cause of disability for individual patients but also a driver of costs for entire healthcare systems. Treatment of pain remains a challenge, and the use of opioids has further led to a concurrent opioid epidemic. In this review, we discuss current standard treatment options for chronic pain, including pharmacological, behavioral, and interventional treatments. In addition, we review ongoing research in different areas that will potentially unlock new therapies.

Keywords: chronic pain; neuromodulation; neuropathic pain; nociceptive pain; nociplastic pain; opioids; pain treatment.

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Conflict of interest statement

Declaration of interests J.W. is a cofounder and scientific advisor for Pallas Technologies, Inc., and is an inventor of a pending US patent application of pain treatment technology.

Figures

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Graphical abstract
See this image and copyright information in PMC

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