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. 2024 Sep 23:51:101204.
doi: 10.1016/j.lanwpc.2024.101204. eCollection 2024 Oct.

Heterogeneity of colistin resistance mechanism in clonal populations of carbapenem-resistant Klebsiella pneumoniae in Vietnam

Bui Tien Sy  1   2 , Sébastien Boutin  3   4 , Le Thi Kieu Linh  1   5 , Simone Weikert-Asbeck  3 , Elias Eger  6 , Susanne Hauswaldt  3 , Truong Nhat My  1 , Nguyen Trong The  1   7 , Jan Rupp  3   4 , Le Huu Song  1   7 , Katharina Schaufler  6   8 , Thirumalaisamy P Velavan  1   5   9   10 , Dennis Nurjadi  1   3   4
Affiliations

Heterogeneity of colistin resistance mechanism in clonal populations of carbapenem-resistant Klebsiella pneumoniae in Vietnam

Bui Tien Sy et al. Lancet Reg Health West Pac. .
No abstract available

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Conflict of interest statement

DN received speaker honoraria from Shionogi and Cepheid outside the scope of this work. All other authors declared no conflicts of interest. The funding sources were not involved in the design, implementation or analysis of the study or in the writing of the decision to submit it for publication.

Figures

Fig. 1
Fig. 1
Phylogeny of carbapenem-resistant Klebsiella pneumoniae in Vietnam. Phylogeny was calculated based on the core-genome (3878 genes present in all isolates) and corrected for recombination using Gubbins. Isolate phenotypically presenting colistin resistance (MIC ≥4 mg/L) are symbolised by triangle while sensitive isolates are symbolised by dots. The circles represent from inner to outside: 1) the presence of mcr genes, 2) mutations within mgrB gene, 3) mutations in other genes associated with colistin resistance, 4) Carbapenemase genes present in the isolates. Abbreviation: AST, antibiotic susceptibility testing.
See this image and copyright information in PMC

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