Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2024;16(19-20):1265-1268.
doi: 10.1080/17501911.2024.2410693. Epub 2024 Oct 10.

Exploring the role of EZH2 modulation in shaping the tumor microenvironment

Affiliations
Editorial

Exploring the role of EZH2 modulation in shaping the tumor microenvironment

Irene Fischetti et al. Epigenomics. 2024.
No abstract available

Keywords: EZH2 inhibitors; cancer therapy; epigenetic modulation; immune system; tumor microenvironment.

PubMed Disclaimer

Conflict of interest statement

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

References

    1. Flavahan WA, Gaskell E, Bernstein BE. Epigenetic plasticity and the hallmarks of cancer. Science. 2017;357(6348):eaal2380 1–8. doi: 10.1126/science.aal2380 - DOI - PMC - PubMed
    1. Loh CH, Veenstra GJC. The role of polycomb proteins in cell lineage commitment and embryonic development. Epigenomes. 2022;6(3):23. doi: 10.3390/epigenomes6030023 - DOI - PMC - PubMed
    1. Kaur P, Shankar E, Gupta S. EZH2-mediated development of therapeutic resistance in cancer. Cancer Lett. 2024;586:216706. doi: 10.1016/j.canlet.2024.216706 - DOI - PubMed
    1. Varambally S, Dhanasekaran SM, Zhou M, et al. The polycomb group protein EZH2 is involved in progression of prostate cancer. Nature. 2002;419(6907):624–629. doi: 10.1038/nature01075 - DOI - PubMed
    1. Hu S, Yu LL, Li ZM, et al. Overexpression of EZH2 contributes to acquired cisplatin resistance in ovarian cancer cells in vitro and in vivo. Cancer Biol Ther. 2010;10(8):788–795. doi: 10.4161/cbt.10.8.12913 - DOI - PubMed

Publication types

LinkOut - more resources