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. 2025 Mar;131(3):514-526.
doi: 10.1002/jso.27921. Epub 2024 Oct 10.

The landscape of Functional Outcome Measures Used in Patients with Bone Sarcoma of the Lower Extremity or Pelvis: A Systematic Review

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The landscape of Functional Outcome Measures Used in Patients with Bone Sarcoma of the Lower Extremity or Pelvis: A Systematic Review

Leonie G Tigelaar et al. J Surg Oncol. 2025 Mar.

Abstract

This systematic review provides a structured overview of the measurement instruments of functional outcome used in lower extremity and pelvic bone sarcoma patients. We identified 42 unique instruments covering 18 distinct functional outcome constructs with most studies measuring constructs within the activity domain of the International Classification of Functioning, disability, and health. The MusculoSkeletal Tumor Society 1993 and 1987 score, Toronto Extremity Salvage Score, and range of motion instruments were the measurement instruments most commonly used.

Keywords: International Classification of Functioning, Disability and Health; functional status; neoplasms, bone tissue; outcome assessment, health care.

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