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Review
. 2024 Nov;44(4):725-736.
doi: 10.1016/j.iac.2024.08.004. Epub 2024 Sep 6.

Biologics in Asthma: Potential to Achieve Clinical Remission

Orlando Rivera 2nd  1 , Rohit Katial  1 , Flavia C L Hoyte  2
Affiliations
Review

Biologics in Asthma: Potential to Achieve Clinical Remission

Orlando Rivera 2nd et al. Immunol Allergy Clin North Am. 2024 Nov.

Abstract

Establishing a universal definition for asthma remission has the potential to improve asthma outcomes and advance research. However, there is still no consensus definition despite broad multidisciplinary efforts to achieve this goal. This study explores the evolving concept of asthma remission, emphasizing the potential of biologics to achieve this state. We will discuss various proposed definitions of asthma remission, international guidelines, and studies evaluating the effectiveness of biologics at achieving clinical remission. We highlight the need for a consensus definition of asthma remission to standardize treatment goals and improve patient outcomes.

Keywords: Asthma; Benralizumab; Biologics; Dupilumab; Mepolizumab; Remission; Tezepelumab.

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Conflict of interest statement

Disclosure R.K. Katial: AstraZeneca: Advisory, speaking; Sanofi/Regeneron: Advisory, speaking; GSK: Advisory. F.C.L. Hoyte: AstraZeneca: Advisory, speaking; GSK: Advisory; Genentech: Advisory; Teva: Advisory; Sanofi: Advisory.

References