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. 2024 Nov;44(6):453-460.
doi: 10.1016/j.annpat.2024.09.004. Epub 2024 Oct 10.

[Calcifications and phosphocalcic metabolism]

[Article in French]
Affiliations

[Calcifications and phosphocalcic metabolism]

[Article in French]
Marie-Françoise Heymann. Ann Pathol. 2024 Nov.

Abstract

Extraosseous calcifications correspond to ubiquitous deposits of intra-tissue calcium salts leading to dysfunction of the affected tissue or organ. There are two types: metastatic calcifications and dystrophic calcifications. Their formation mechanism is by mimicking the physiological mineralization process with an "osteoblast-like" cell. The cause of extra-osseous calcification is variable and depends on risk factors. If the subject is young, you will have to think about a genetic syndrome!

Keywords: Atherosclerosis; Athérosclérose; Calcification dystrophique; Calcification extra osseuse; Calcification métastatique; Calcification tumorale; Cellule osteoblast like; Deposit; Dystrophic calcification; Dépôt; Extraosseous calcification; Metastatic calcification; Osteoblast like cell; Tumor calcification.

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