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. 2024 Oct 4;5(10):e243391.
doi: 10.1001/jamahealthforum.2024.3391.

Competition in International Generic Drug Markets

Étienne Gaudette  1   2 , Shirin Rizzardo  2 , Kevin R Pothier  2 , Mina Tadrous  3   4
Affiliations

Competition in International Generic Drug Markets

Étienne Gaudette et al. JAMA Health Forum. .
No abstract available

Plain language summary

This cross-sectional study compares the small molecule generic drug markets of a group of high-income countries with similar pharmaceutical regulatory environments.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Gaudette, Mrs Rizzardo, and Mr Pothier are employees of the Patented Medicine Prices Review Board, an independent quasi-judicial agency of the Government of Canada. Dr Tadrous reported personal fees from Health Canada and Canada’s Drug Agency outside the submitted work.

Figures

Figure 1.
Figure 1.. Generic Manufacturers Selling 25 or More Generic Drugs, 2010-2022
The threshold of 25 or more was chosen to count manufacturers with a considerable portfolio of drugs. Manufacturer names featuring suffixes and regional designations were truncated to avoid double counting (eg, Fresenius Medi.Jap was replaced with Fresenius). Generic company counts did not group subsidiaries and parent companies except for cases where the source data identified the subsidiary status in the company’s name.
Figure 2.
Figure 2.. Proportion of Off-Patent Drugs in Dominated and Monopoly Markets, 2010-2022
The share of off-patent drugs for which the units sold (either flagged as generic or brand) by 1 company represented 50% or more (dominated markets) and 100% (monopoly markets) of total units sold. In each country, all off-patent drugs with sales were included in the calculations. A drug was considered off patent if at least 1 country recorded a sale for it categorized as generic in the source data.
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References

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