Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Jan 20;14(1):piae109.
doi: 10.1093/jpids/piae109.

Anaerobe-Targeted Antibiotic Therapy in the Neonatal Intensive Care Unit

Matthew B Green  1 , Alvaro Zevallos Barboza  2 , Sagori Mukhopadhyay  2   3 , Jeffrey S Gerber  3   4 , Michael J Morowitz  5 , Karen M Puopolo  2   3 , Dustin D Flannery  2   3
Affiliations

Anaerobe-Targeted Antibiotic Therapy in the Neonatal Intensive Care Unit

Matthew B Green et al. J Pediatric Infect Dis Soc. .

Abstract

Anaerobe-targeted antibiotic (ATA) therapy may adversely impact the developing neonatal microbiome. We describe utilization patterns, potential indications, and related outcomes of ATA therapy in neonatal intensive care units across the United States over 13 years. While overall antibiotic use decreased, ATA use was unchanged. Potentially associated indications were inconsistent.

Keywords: anaerobic; antibiotic; bacteria; neonatal; prematurity.

PubMed Disclaimer

Substances