Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Oct 11;5(10):1200-1202.
doi: 10.1016/j.medj.2024.08.008.

Twice-yearly lenacapavir: A milestone for HIV prevention in young African women

Silvia Nozza  1 , Antonella Castagna  2
Affiliations

Twice-yearly lenacapavir: A milestone for HIV prevention in young African women

Silvia Nozza et al. Med. .

Abstract

The PURPOSE 1 trial1 demonstrated that after 52 weeks, no cisgender women acquired HIV infection after receiving subcutaneous twice-yearly lenacapavir. HIV incidence with lenacapavir was significantly lower than HIV incidence with daily oral emtricitabine/tenofovir alafenamide (F/TAF) or daily oral emtricitabine/tenofovir disoproxil fumarate (F/TDF). It is the first pre-exposure prophylaxis regimen with 100% efficacy in young women.

PubMed Disclaimer

Conflict of interest statement

Declaration of interests The authors declare no conflicts of interest.

MeSH terms

LinkOut - more resources