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Meta-Analysis
. 2024 Oct 12;19(1):649.
doi: 10.1186/s13018-024-05099-8.

Incidence of periprosthetic joint infection after primary total knee arthroplasty shows significant variation : a synthesis of meta-analysis and bibliometric analysis

Tao Ma  1 , Jun Jiao  1 , Da-Wei Guo  1 , Shu-Zheng Lv  1 , Di Zhang  1 , De-Cai Hou  2
Affiliations
Meta-Analysis

Incidence of periprosthetic joint infection after primary total knee arthroplasty shows significant variation : a synthesis of meta-analysis and bibliometric analysis

Tao Ma et al. J Orthop Surg Res. .

Abstract

Total Knee Arthroplasty (TKA) is a surgery that is commonly performed on older adults to improve their quality of life. However, the increasing use of knee joint prostheses has led to a rise in the incidence of Prosthetic Joint Infections (PJI) in patients after TKA. Different clinical studies have looked at the occurrence of PJI after TKA in different regions, but they have drawn varying conclusions. To better understand this topic, we conducted a meta-analysis and bibliometric study using data from multiple databases. Our research found that the estimated prevalence of PJI after TKA is approximately 1.08% across different regions, but there is still considerable variation. Additionally, our regression analysis of sub-groups shows significant differences in follow-up periods. Furthermore, our comprehensive bibliometric analysis identifies current research trends, "hotspots" related to TKA-related PJI, influential nations, organizations, and noteworthy publications. Our analysis provides valuable insights to guide future research in this area.

Keywords: Bibliometric analysis; Epidemiology; Incidence; Meta-analysis; Periprosthetic joint infection; Total knee arthroplasty.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Candidate study selection workflow for metaanalysis
Fig. 2
Fig. 2
Forest plot of the overall incidence of PJI in the database-based studies. The size of the squares represents the proportion (95% CI) for each of the studies. The size of the diamonds represent the overall proportion (95% CI)
Fig. 3
Fig. 3
The Meta-regression analysis
Fig. 4
Fig. 4
Incidence of PJI from a single institution or database
Fig. 5
Fig. 5
Annual publication numbers from 1994 to 2023
Fig. 6
Fig. 6
A network visualization of author keywords; B visualisation map summarising the themes of the previous years from a temporal point of view; C Visualisation maps of different research branch networks; D Popular Hot Topic Words of the Past Years
See this image and copyright information in PMC

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