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Randomized Controlled Trial
. 2024 Nov 1;29(6):e843-e849.
doi: 10.4317/medoral.26818.

Evaluation of a new mouthwash formulated with Chlorhexidine and Cymenol after a scaling and root planing treatment in grade I and II periodontal patients

P Hermida-Cabrera  1 , F Aguilera, F Vivancos-Cuadras, L Ferrá-Domingo, D Torres-Lagares, J Gutiérrez-Pérez, T Pereira-Riveros, T Vinuesa, M-A Serrera-Figallo, M Baus-Domínguez
Affiliations
Randomized Controlled Trial

Evaluation of a new mouthwash formulated with Chlorhexidine and Cymenol after a scaling and root planing treatment in grade I and II periodontal patients

P Hermida-Cabrera et al. Med Oral Patol Oral Cir Bucal. .

Abstract

Background: Periodontal disease is a multifactorial pathology whose treatment protocol is becoming increasingly standardized, relying, among others, on adjuvant therapies. This study aims to determine the efficacy of a new chlorhexidine compound compared with the gold standard 0.12% chlorhexidine during periodontal maintenance of a patient with periodontitis grade I or II after scaling and root planing treatment.

Material and methods: A parallel, randomized, double-blind clinical trial with two arms: (A) treatment with 0.12% chlorhexidine mouthwash; (B) treatment with new chlorhexidine mouthwash containing O-Cymen-5-Ol. The patient was examined: (D0) initial examination, (D7) clinical examination one week after treatment, (D14) clinical examination two weeks after treatment and (D28) clinical examination three weeks after treatment. They are collecting the following data: Plaque index (PI), gingival index (GI), bleeding index (BoP), pocket depth (PS), and attachment loss (CAL).

Results: After a follow-up of 43 patients, no statistically significant differences were found between the groups at any of the times or for any of the parameters evaluated, meeting the predefined criteria of non-inferiority.

Conclusions: The new chlorhexidine mouthwash proved to be non-inferior to 0.12% chlorhexidine in terms of efficacy during short-term periodontal maintenance after scaling and root planing.

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Conflict of interest statement

The authors declare no conflict of interest, financial or otherwise.

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