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Case Reports
. 1985 Sep-Oct;1(5):317-9.
doi: 10.1016/0887-8994(85)90037-2.

Valproic acid in the treatment of Sydenham chorea

L A Alvarez  1 , G Novak
Affiliations
Case Reports

Valproic acid in the treatment of Sydenham chorea

L A Alvarez et al. Pediatr Neurol. 1985 Sep-Oct.

Abstract

Severe cases of Sydenham chorea are still difficult to manage because optimal therapy has not been found. In this report severe chorea responded to valproic acid therapy after trials with diazepam and haloperidol had failed. The literature is reviewed and the possible mechanism of action of valproate in this movement disorder is discussed. Valproic acid is proposed as an effective treatment for severe cases of Sydenham chorea.

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