Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Nov 14;45(43):4658-4660.
doi: 10.1093/eurheartj/ehae657.

Steps towards curing Yentl syndrome: appraising sex differences in circulating proteins and incident myocardial infarction

Affiliations

Steps towards curing Yentl syndrome: appraising sex differences in circulating proteins and incident myocardial infarction

Anna K Barton et al. Eur Heart J. .
No abstract available

PubMed Disclaimer

Figures

Graphical Abstract
Graphical Abstract
Mechanisms of myocardial infarction in females have focused on sex differences in traditional risk factors and female-specific risk factors. Future focus includes (1) evaluating sex-differences in mechanisms in MI, (2) biologic profiling, (3) Equitable representation of females in CVD research, and (4) further mechanistic and therapeutic research into MI subtypes that disproportionately affect women. CVD, cardiovascular disease; MI, myocardial infarction; MINOCA, myocardial infarction with no obstructive coronary arteries; SCAD, spontaneous coronary artery dissection.

References

    1. Healy B. The Yentl syndrome. N Engl J Med 1991;325:274–6. 10.1056/NEJM199107253250408 - DOI - PubMed
    1. Lau ES, Paniagua SM, Guseh JS, Bhambhani V, Zanni MV, Courchesne P, et al. Sex differences in circulating biomarkers of cardiovascular disease. J Am Coll Cardiol 2019;74:1543–53. 10.1016/j.jacc.2019.06.077 - DOI - PMC - PubMed
    1. Lew J, Sanghavi M, Ayers CR, McGuire DK, Omland T, Atzler D, et al. Sex-based differences in cardiometabolic biomarkers. Circulation 2017;135:544–55. 10.1161/CIRCULATIONAHA.116.023005 - DOI - PMC - PubMed
    1. Titova OE, Yuan S, Byberg L, Baron JA, Lind L, Michaëlsson K, et al. Plasma proteome and incident myocardial infarction: sex-specific differences. Eur Heart J 2024;45:4647–57. 10.1093/eurheartj/ehae658 - DOI - PMC - PubMed
    1. Tan ESJ, Oon YY, Chan SP, Liew OW, Chong JPC, Tay E, et al. Novel predictive role for mid-regional proadrenomedullin in moderate to severe aortic stenosis. Heart 2022;108:1319–27. 10.1136/heartjnl-2021-320707 - DOI - PubMed

Grants and funding