Review

. 2024 Aug 19;4(3):269-292.

doi: 10.1007/s43657-023-00142-w. eCollection 2024 Jun.

Expert Consensus on Big Data Collection of Skin and Appendage Disease Phenotypes in Chinese

Shuang Zhao^#¹, Zhongling Luo^#¹, Ying Wang^#¹, Xinghua Gao², Juan Tao³, Yong Cui⁴, Aijun Chen⁵, Daxing Cai⁶, Yan Ding⁷, Heng Gu⁸, Jianying Gu⁹, Chao Ji¹⁰, Xiaojing Kang¹¹, Qianjin Lu¹², Chengzhi Lv¹³, Min Li¹⁴, Wei Li¹⁵, Wei Liu¹⁶, Xia Li¹⁷, Yuzhen Li¹⁸, Xiaoyong Man¹⁹, Jianjun Qiao²⁰, Liangdan Sun²¹, Yuling Shi²², Wenyu Wu²³, Jianxin Xia²⁴, Rong Xiao²⁵, Bin Yang²⁶, Yehong Kuang¹, Zeyu Chen²⁷, Jingyue Fang²⁸, Jian Kang²⁹, Minghui Yang³⁰, Mi Zhang¹, Juan Su¹, Xuejun Zhang¹⁴, Xiang Chen¹

Affiliations

¹ Department of Dermatology, Xiangya Hospital, Central South University, Changsha, 410083 China.
² Department of Dermatology, No. 1 Hospital of China Medical University and Key Laboratory of Immunodermatology, Ministry of Health and Ministry of Education, Shenyang, 110001 China.
³ Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (HUST), Wuhan, 430022 China.
⁴ Department of Dermatology, China-Japan Friendship Hospital, Beijing, 100000 China.
⁵ Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016 China.
⁶ Department of Dermatology, Qilu Hospital, Shandong University, Jinan, 250000 China.
⁷ Department of Dermatology, Hainan General Hospital, Haikou, 570102 China.
⁸ Institute of Dermatology, Chinese Academy of Medical Sciences, Nanjing, 210042 China.
⁹ Department of Plastic Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032 China.
¹⁰ Department of Dermatology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, 350000 China.
¹¹ Department of Dermatology, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, 830001 China.
¹² Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, 210000 China.
¹³ Department of Dermatology, Dalian Skin Disease Hospital, Liaoning, 116021 China.
¹⁴ Department of Dermatology, Dushu Lake Hospital Affiliated to Soochow University (Medical Center of Soochow University, Suzhou Dushu Lake Hospital), Suzhou, 215000 China.
¹⁵ School of Aeronautics and Astronautics, Sichuan University, Chengdu, 610000 China.
¹⁶ Department of Dermatology, General Hospital of Air Force, Beijing, 100000 China.
¹⁷ Department of Dermatology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025 China.
¹⁸ Department of Dermatology, The Second Affiliated Hospital of Harbin Medical University, Harbin, 150000 China.
¹⁹ Department of Dermatology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310000 China.
²⁰ Department of Dermatology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310000 China.
²¹ Department of Dermatology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230000 China.
²² Department of Dermatology, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, 200443 China.
²³ Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, 200443 China.
²⁴ Department of Dermatology, The Second Affiliated Hospital of JiLin University, Changchun, 130000 China.
²⁵ Department of Dermatology, Second Xiangya Hospital, Central South University, Changsha, 410083 China.
²⁶ Dermatology Hospital, Southern Medical University, Guangzhou, 510091 China.
²⁷ School of Materials Science and Engineering, Central South University, Changsha, 410083 China.
²⁸ School of Physics and Electronics, Central South University, Changsha, 410083 China.
²⁹ Department of Dermatology, The Third Xiangya Hospital of Central South University, Changsha, 410083 China.
³⁰ College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083 China.

^# Contributed equally.

PMID: 39398426
PMCID: PMC11466921
DOI: 10.1007/s43657-023-00142-w

Review

Expert Consensus on Big Data Collection of Skin and Appendage Disease Phenotypes in Chinese

Shuang Zhao et al. Phenomics. 2024.

. 2024 Aug 19;4(3):269-292.

doi: 10.1007/s43657-023-00142-w. eCollection 2024 Jun.

Authors

Affiliations

¹ Department of Dermatology, Xiangya Hospital, Central South University, Changsha, 410083 China.
² Department of Dermatology, No. 1 Hospital of China Medical University and Key Laboratory of Immunodermatology, Ministry of Health and Ministry of Education, Shenyang, 110001 China.
³ Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (HUST), Wuhan, 430022 China.
⁴ Department of Dermatology, China-Japan Friendship Hospital, Beijing, 100000 China.
⁵ Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016 China.
⁶ Department of Dermatology, Qilu Hospital, Shandong University, Jinan, 250000 China.
⁷ Department of Dermatology, Hainan General Hospital, Haikou, 570102 China.
⁸ Institute of Dermatology, Chinese Academy of Medical Sciences, Nanjing, 210042 China.
⁹ Department of Plastic Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200032 China.
¹⁰ Department of Dermatology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, 350000 China.
¹¹ Department of Dermatology, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, 830001 China.
¹² Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, 210000 China.
¹³ Department of Dermatology, Dalian Skin Disease Hospital, Liaoning, 116021 China.
¹⁴ Department of Dermatology, Dushu Lake Hospital Affiliated to Soochow University (Medical Center of Soochow University, Suzhou Dushu Lake Hospital), Suzhou, 215000 China.
¹⁵ School of Aeronautics and Astronautics, Sichuan University, Chengdu, 610000 China.
¹⁶ Department of Dermatology, General Hospital of Air Force, Beijing, 100000 China.
¹⁷ Department of Dermatology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025 China.
¹⁸ Department of Dermatology, The Second Affiliated Hospital of Harbin Medical University, Harbin, 150000 China.
¹⁹ Department of Dermatology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310000 China.
²⁰ Department of Dermatology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310000 China.
²¹ Department of Dermatology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230000 China.
²² Department of Dermatology, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, 200443 China.
²³ Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, 200443 China.
²⁴ Department of Dermatology, The Second Affiliated Hospital of JiLin University, Changchun, 130000 China.
²⁵ Department of Dermatology, Second Xiangya Hospital, Central South University, Changsha, 410083 China.
²⁶ Dermatology Hospital, Southern Medical University, Guangzhou, 510091 China.
²⁷ School of Materials Science and Engineering, Central South University, Changsha, 410083 China.
²⁸ School of Physics and Electronics, Central South University, Changsha, 410083 China.
²⁹ Department of Dermatology, The Third Xiangya Hospital of Central South University, Changsha, 410083 China.
³⁰ College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083 China.

^# Contributed equally.

PMID: 39398426
PMCID: PMC11466921
DOI: 10.1007/s43657-023-00142-w

Abstract

The collection of big data on skin and appendage phenotypes has revolutionized the field of personalized diagnosis and treatment by enabling the evaluation of individual characteristics and early detection of abnormalities. To establish a standardized system for collecting and measuring big data on phenotypes, a systematic categorization of measurement entries has been undertaken, accompanied by recommendations on measurement entries, environmental equipment requirements, and collection processes, tailored to the needs of different usage scenarios. Specific collection sites have also been recommended based on different index characteristics. A multi-center, multi-regional collaboration has been initiated to collect big date on phenotypes of healthy and diseased skin in the Chinese population. This data will be correlated with patient disease information, exploring the factors influencing skin phenotype, analyzing the phenotypic data features that can predict prognosis, and ultimately promoting the exploration of the pathophysiology and pathogenesis of skin diseases and therapeutic approaches. Non-invasive skin measurement robots are also in development. This consensus aims to provide a reference for the study of phenomics and the standardization of phenotypic measurements of skin and appendages in China.

Keywords: Big data; Disease phenotype; Skin and appendages; Standardized system.

© International Human Phenome Institutes (Shanghai) 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

PubMed Disclaimer

Conflict of interest statement

Conflict of interestOn behalf of all authors, the corresponding authors state that there is no conflict of interest.

Figures

**Fig. 1**
Systematic grouping of skin and appendage phenotypic measurement entries

**Fig. 2**
Measurement tools commonly used in clinical diagnosis and treatment work

**Fig. 3**
Dermatology clinical imaging data acquisition scene

**Fig. 4**
Skin and appendage phenotype data collection sites—physiological indicators

See this image and copyright information in PMC

References

1. Achs R, Harper RG, Harrick NJ (1966) Unusual dermatolyphics associated with major congenital malformations. N Engl J Med 275(23):1273–1278. 10.1056/nejm196612082752303 - PubMed
1. Agache P (2004) Thermometry and remote thermography. In: Handbook of Measuring the skin 1st edn. Berlin: Springer, pp 354–362
1. Alexander H, Brown S, Danby S et al (2018) Research Techniques Made Simple: Transepidermal Water Loss Measurement as a Research Tool. J Invest Dermatol 138(11):2295-2300.e2291. 10.1016/j.jid.2018.09.001 - PubMed
1. Arsiwala SZ, Desai SR (2019) Fractional Carbon Dioxide Laser: Optimizing Treatment Outcomes for Pigmented Atrophic Acne Scars in Skin of Color. J Cutan Aesthet Surg 12(2):85–94. 10.4103/jcas.Jcas_171_18 - PMC - PubMed
1. Bajpai VK, Swigut T, Mohammed J et al (2023) A genome-wide genetic screen uncovers determinants of human pigmentation. Science (new York, NY) 381(6658):eade6289. 10.1126/science.ade6289 - PMC - PubMed

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Expert Consensus on Big Data Collection of Skin and Appendage Disease Phenotypes in Chinese

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Expert Consensus on Big Data Collection of Skin and Appendage Disease Phenotypes in Chinese

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