Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Meta-Analysis
. 2024 Dec 31;20(1):2402122.
doi: 10.1080/21645515.2024.2402122. Epub 2024 Oct 14.

Healthcare worker practices for HPV vaccine recommendation: A systematic review and meta-analysis

Damola Bakare  1 , Elisa Gobbo  2 , Kofoworola O Akinsola  3 , Ayobami A Bakare  2   4 , Julius Salako  1 , Claudia Hanson  2   5   6 , Sibylle Herzig van Wees  2 , Adegoke Falade  1   3 , Carina King  2
Affiliations
Meta-Analysis

Healthcare worker practices for HPV vaccine recommendation: A systematic review and meta-analysis

Damola Bakare et al. Hum Vaccin Immunother. .

Abstract

Healthcare workers (HCWs) are trusted sources of information for vaccination and their attitude toward vaccination is thus critical. We aimed to synthesize existing literature on healthcare workers' HPV vaccine confidence and their practices of recommending this vaccine. We conducted a systematic literature review and meta-analysis, with the search conducted last in March 2024. For the inclusion criteria, the studies needed to include healthcare worker practices or behaviors on recommending the HPV vaccination. Seventy-three articles were included. The proportions of HCWs recommending varied considerably by region and gender of the recipient, but there was no statistically significant difference in income level or pre- or post-HPV vaccine introduction into the national vaccination program. The main barriers to recommending HPV vaccination were concerns around safety and efficacy, cost, parental concerns, and systemic barriers. The results illustrate the importance of contextually adapted approaches to improving vaccine acceptance and recommendation.

Keywords: Human papillomavirus; healthcare workers; meta-analysis; recommendation behavior; systematic review; vaccine confidence.

PubMed Disclaimer

Conflict of interest statement

No potential conflict of interest was reported by the author(s).

Figures

Figure 1.
Figure 1.
PRISMA flow diagram for systematic review article inclusion.
Figure 2.
Figure 2.
Global map with number of articles per country (MapChart)*.
Figure 3.
Figure 3.
Proportion of healthcare workers recommendation behavior (practice) for both boys and girls (n = 35).
Figure 4.
Figure 4.
Proportion of healthcare workers recommendation willingness (intent) for both boys and girls (n = 24).
Figure 5.
Figure 5.
Bar chart of overall proportion for the sub-analyses of WHO region, income level, HPV introduction time, and gender.
Figure 6.
Figure 6.
Cited barriers to recommending HPV (n=55).
See this image and copyright information in PMC

References

    1. World Health Organization. World Health Organization . Human papillomavirus and cancer. 2023. [accessed 2023 Nov 21]. https://www.who.int/news-room/fact-sheets/detail/human-papilloma-virus-a....
    1. Burmeister CA, Khan SF, Schäfer G, Mbatani N, Adams T, Moodley J, Prince S.. Cervical cancer therapies: current challenges and future perspectives. Tumour Virus Res. 2022. June;13:200238. doi:10.1016/j.tvr.2022.200238. - DOI - PMC - PubMed
    1. Buskwofie A, David-West G, Clare CA. A review of cervical cancer: incidence and disparities. J Natl Med Assoc. 2020. Apr;112(2):229–13. doi:10.1016/j.jnma.2020.03.002. - DOI - PubMed
    1. Singh D, Vignat J, Lorenzoni V, Eslahi M, Ginsburg O, Lauby-Secretan B, Arbyn M, Basu P, Bray F, Vaccarella S. Global estimates of incidence and mortality of cervical cancer in 2020: a baseline analysis of the WHO global cervical cancer elimination initiative. Lancet Glob Health [Internet]. 2023. Feb 1 [cited 2023 Nov 6]. 11(2):e197–206. http://www.thelancet.com/article/S2214109X22005010/fulltext. - PMC - PubMed
    1. Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. [2018 Nov 12];68(6):394–424. doi:10.3322/caac.21492. - DOI - PubMed

Publication types

MeSH terms

Substances