Optical Spectroscopic Detection and Typing of Cardiac Amyloidosis

Sudipta S Mukherjee^#¹, Joseph J Maleszewski^#^{2

3}, Daniel Luthringer⁴, Matthew P Confer¹, Anirudh Mittal¹, Surendra Dasari⁵, Ellen D McPhail², Suraj Kapa³, Thenkurussi Kesavadas⁶, Andre Kajdacsy-Balla⁷, Evan Kransdorf⁸, Jai Raman⁹, Rohit Bhargava^{1

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12

13

14

15}

Affiliations

¹ Beckman Institute for Advanced Science and Technology (S.S.M., M.P.C., A.M., R.B.), University of Illinois Urbana-Champaign, Urbana.
² Department of Laboratory Medicine and Pathology (J.J.M., E.D.M.), Mayo Clinic, Rochester, MN.
³ Department of Cardiovascular Medicine (J.J.M., S.K), Mayo Clinic, Rochester, MN.
⁴ Department of Pathology and Laboratory Medicine (D.L.), Cedars-Sinai Medical Center, Los Angeles, CA.
⁵ Department of Quantitative Health Sciences (S.D.), Mayo Clinic, Rochester, MN.
⁶ Division of Research and Economic Development, University at Albany-State University of New York (T.K.).
⁷ Department of Pathology, University of Illinois at Chicago (A.K.-B.).
⁸ Smidt Heart Institute (E.K.), Cedars-Sinai Medical Center, Los Angeles, CA.
⁹ Spectromix Laboratory, University of Melbourne, Fitzroy, Victoria, Australia (J.R.).
¹⁰ Department of Bioengineering (R.B.), University of Illinois Urbana-Champaign, Urbana.
¹¹ Department of Chemical and Biomolecular Engineering (R.B.), University of Illinois Urbana-Champaign, Urbana.
¹² Department of Electrical and Computer Engineering (R.B.), University of Illinois Urbana-Champaign, Urbana.
¹³ Mechanical Science and Engineering (R.B.), University of Illinois Urbana-Champaign, Urbana.
¹⁴ Cancer Center at Illinois (R.B.), University of Illinois Urbana-Champaign, Urbana.
¹⁵ CZ Biohub Chicago, LLC, IL (R.B.).

^# Contributed equally.

Sudipta S Mukherjee et al. Circulation. 2024.

. 2024 Oct 15;150(16):1299-1301.

doi: 10.1161/CIRCULATIONAHA.124.069554. Epub 2024 Oct 14.

¹ Beckman Institute for Advanced Science and Technology (S.S.M., M.P.C., A.M., R.B.), University of Illinois Urbana-Champaign, Urbana.
² Department of Laboratory Medicine and Pathology (J.J.M., E.D.M.), Mayo Clinic, Rochester, MN.
³ Department of Cardiovascular Medicine (J.J.M., S.K), Mayo Clinic, Rochester, MN.
⁴ Department of Pathology and Laboratory Medicine (D.L.), Cedars-Sinai Medical Center, Los Angeles, CA.
⁵ Department of Quantitative Health Sciences (S.D.), Mayo Clinic, Rochester, MN.
⁶ Division of Research and Economic Development, University at Albany-State University of New York (T.K.).
⁷ Department of Pathology, University of Illinois at Chicago (A.K.-B.).
⁸ Smidt Heart Institute (E.K.), Cedars-Sinai Medical Center, Los Angeles, CA.
⁹ Spectromix Laboratory, University of Melbourne, Fitzroy, Victoria, Australia (J.R.).
¹⁰ Department of Bioengineering (R.B.), University of Illinois Urbana-Champaign, Urbana.
¹¹ Department of Chemical and Biomolecular Engineering (R.B.), University of Illinois Urbana-Champaign, Urbana.
¹² Department of Electrical and Computer Engineering (R.B.), University of Illinois Urbana-Champaign, Urbana.
¹³ Mechanical Science and Engineering (R.B.), University of Illinois Urbana-Champaign, Urbana.
¹⁴ Cancer Center at Illinois (R.B.), University of Illinois Urbana-Champaign, Urbana.
¹⁵ CZ Biohub Chicago, LLC, IL (R.B.).

^# Contributed equally.

No abstract available

Keywords: amyloidosis; cardiomyopathies; hemodynamics; machine learning; proteomics.

Conflict of interest statement

None.

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