Toward Enhanced Methodological Rigor: Addressing Limitations in the Comparative Analysis of Probiotics and Antidepressants for Major Depressive Disorder Management

Affiliations

¹ Department of Physiology and Pharmacology, Federal University of Ceara, Fortaleza 60430-275, Brazil.
² Center for Health Sciences, University of Fortaleza, Fortaleza 60430-275, Brazil.
³ Faculty of Medicine, Federal University of Ceara, Fortaleza 60430-275, Brazil.
⁴ Faculty of Medicine, Department of Clinical Medicine, Federal University of Ceara, Fortaleza 60430-275, Brazil.
⁵ Psychiatry Service, Walter Cantidio Teaching Hospital, Federal University of Ceara, Fortaleza 60430-275, Brazil.

Comment

Sergio Andre de Souza Junior et al. Nutr Rev. 2025.

. 2025 May 1;83(5):965-966.

doi: 10.1093/nutrit/nuae117.

¹ Department of Physiology and Pharmacology, Federal University of Ceara, Fortaleza 60430-275, Brazil.
² Center for Health Sciences, University of Fortaleza, Fortaleza 60430-275, Brazil.
³ Faculty of Medicine, Federal University of Ceara, Fortaleza 60430-275, Brazil.
⁴ Faculty of Medicine, Department of Clinical Medicine, Federal University of Ceara, Fortaleza 60430-275, Brazil.
⁵ Psychiatry Service, Walter Cantidio Teaching Hospital, Federal University of Ceara, Fortaleza 60430-275, Brazil.

No abstract available

Comment on

Probiotics for adults with major depressive disorder compared with antidepressants: a systematic review and network meta-analysis.
Zhao S, Liang S, Tao J, Peng Y, Chen S, Wai HKF, Chung FY, Sin ZY, Wong MKL, Haqq AM, Chang WC, Ni MY, Chan FKL, Ng SC, Tun HM. Zhao S, et al. Nutr Rev. 2025 Jan 1;83(1):72-82. doi: 10.1093/nutrit/nuad171. Nutr Rev. 2025. PMID: 38219239