Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Oct 15;18(1):99.
doi: 10.1007/s12105-024-01709-3.

SNRPE, an Oncofetal Protein: can be a Diagnostic Marker and Therapeutic Target for Oral Cancers?

Somasundaram Sanjay  1 , Muthusethupathi Sharmila  1 , Devaraj Ezhilarasan  2
Affiliations

SNRPE, an Oncofetal Protein: can be a Diagnostic Marker and Therapeutic Target for Oral Cancers?

Somasundaram Sanjay et al. Head Neck Pathol. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
The probable tumorigenic potential of small nuclear ribonucleoprotein polypeptide E (SNRPE) via fibroblast growth factor receptor 4 (FGFR4) mediated signaling in oral cancer. Oral cancer cells likely have increased SNRPE oncofetal proteins, which could activate FGFR4 receptors on cancer cells, thereby promoting metastasis
See this image and copyright information in PMC

References

    1. van der Waal I (2009) Potentially malignant disorders of the oral and oropharyngeal mucosa; terminology, classification and present concepts of management. Oral Oncol 45(4–5):317–323 - PubMed
    1. Deshmukh A, Rao KN, Arora RD, Nagarkar NM, Singh A, Shetty OS (2022) Molecular insights into oral malignancy. Indian J Surg Oncol 13(2):267–280 - PMC - PubMed
    1. Pulte D, Brenner H (2010) Changes in survival in head and neck cancers in the late 20th and early 21st century: a period analysis. Oncologist 15(9):994–1001 - PMC - PubMed
    1. Usman S, Jamal A, Teh MT, Waseem A (2021) Major Molecular Signaling pathways in oral Cancer Associated with Therapeutic Resistance. Front Oral Health 1:603160 - PMC - PubMed
    1. Wu Q, Liao R, Miao C et al (2024) Oncofetal SNRPE promotes HCC tumorigenesis by regulating the FGFR4 expression through alternative splicing. Br J Cancer 131(1):77–89 - PMC - PubMed

Substances

LinkOut - more resources