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. 2024 Jan-Dec:21:14799731241291067.
doi: 10.1177/14799731241291067.

Effect of a nurse-led integrated care intervention on quality of life and rehospitalisation in patients with severe exacerbation of COPD-a pilot study

Gabriela Schmid-Mohler  1   2 , Christine Hübsch  1   2 , Julia Braun  3 , Claudia Steurer-Stey  3   4 , Celine Aregger  5 , Dominik J Schaer  6   7 , Christian Clarenbach  2   7
Affiliations

Effect of a nurse-led integrated care intervention on quality of life and rehospitalisation in patients with severe exacerbation of COPD-a pilot study

Gabriela Schmid-Mohler et al. Chron Respir Dis. 2024 Jan-Dec.

Abstract

Objective: To explore the feasibility and effect of a nurse-led integrated care intervention on health-related quality of life (QoL) and unplanned 90-day rehospitalisation in patients hospitalised due to acute exacerbation of COPD (AECOPD).

Method: A monocentric non-randomized parallel cluster design was applied. The primary endpoint was the difference between Chronic Respiratory Questionnaire (CRQ) Mastery Scores at hospital discharge and 13 weeks post-discharge. Secondary endpoints were differences between other CRQ scores, numbers of rehospitalisations and self-reported exacerbations. The study would end either 13 weeks after the full sample size was achieved or when study time ran out.

Results: The study was terminated before reaching the targeted sample size. Of 174 invitees, 69 (39.7%, 30 control, 39 intervention) consented to participate. Of those, 47 completed the study, 45 of whom had complete data sets for the primary endpoint. No differences in QoL scores, unplanned COPD-related rehospitalisations or unplanned all-cause rehospitalisations were detected. The mean number of self-reported moderate exacerbations was higher in the intervention group (p = 0.006).

Conclusion: The pilot study had slow recruitment, high drop-out rates, and no significant effect on 3-month outcomes. Further research should focus on enhancing the current understanding of how to motivate and recruit patients in this setting.

Clinicaltrials.gov id: NCT04011332.

Keywords: COPD; Patient readmission; nursing; pilot studies; quality of life; self-management.

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Conflict of interest statement

Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Study process on cluster level.
Figure 2.
Figure 2.
Study process for patients in the control and intervention phase.
Figure 3.
Figure 3.
Flowchart.
See this image and copyright information in PMC

References

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