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Review
. 2024 Sep 27;13(19):5778.
doi: 10.3390/jcm13195778.

Therapeutic Potential of Gum Arabic (Acacia senegal) in Chronic Kidney Disease Management: A Narrative Review

Sami Alobaidi  1
Affiliations
Review

Therapeutic Potential of Gum Arabic (Acacia senegal) in Chronic Kidney Disease Management: A Narrative Review

Sami Alobaidi. J Clin Med. .

Abstract

Chronic kidney disease (CKD) poses significant health challenges globally, particularly in regions like the Middle East. This review evaluates the potential efficacy and safety of Gum Arabic (Acacia senegal), a traditional remedy, in managing CKD. A comprehensive literature review was conducted using databases including PubMed and Scopus, focusing on the biochemical, physiological, and therapeutic impacts of Gum Arabic on renal health. Gum Arabic has demonstrated antioxidative and anti-inflammatory properties that may benefit renal function, as shown in animal studies. Clinical trials suggest improvements in renal biomarkers, though these are limited by scope and methodology. While promising, the clinical application of Gum Arabic requires cautious interpretation due to gaps in understanding its mechanisms of action. Gum Arabic shows potential as an adjunct treatment for CKD, reflecting both traditional use and preliminary scientific evidence. Future research should focus on its long-term efficacy, safety, and underlying biochemical pathways to better guide its therapeutic use.

Keywords: Acacia senegal; chronic kidney disease; gum arabic; renal health; traditional medicine.

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Conflict of interest statement

The author declares no conflict of interest.

Figures

Figure 1
Figure 1
Biochemical pathways of Gum Arabic’s impact on gut microbiota and renal protection. Up arrow, increase.
See this image and copyright information in PMC

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