Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Oct 8;13(19):5998.
doi: 10.3390/jcm13195998.

Sex-Based Differences in Polytraumatized Patients between 1995 and 2020: Experiences from a Level I Trauma Center

Affiliations

Sex-Based Differences in Polytraumatized Patients between 1995 and 2020: Experiences from a Level I Trauma Center

Valerie Weihs et al. J Clin Med. .

Abstract

Background/Objectives: The aim of this study was to examine sex-related differences in the outcomes of polytraumatized patients admitted to a level I trauma center. Methods: This was a retrospective data analysis of 980 consecutive polytraumatized patients admitted to a single level I trauma center between January 1995 and December 2020. Results: Among all patients, about 30% were female, with a significantly higher age and significantly higher rates of suicidal attempts. No sex-related differences regarding injury severity or trauma mechanisms could be seen, but female patients had significantly higher overall in-hospital mortality rates compared to male patients. Even in the elderly group of patients, elderly female patients were significantly older compared to elderly male patients, with significantly increased lengths of hospital stay. In the elderly group of patients, no sex-related differences regarding injury severity, trauma mechanisms or mortality could be detected. Multivariate analysis revealed suicidal attempt, severe head injury and age > 54 years as independent prognostic factors in the survival of polytraumatized patients. Conclusions: Distinctive sex-related differences can be found, with female polytraumatized patients being significantly older and having higher overall mortality rates with significantly increased LOS. Our study suggests a strong sex-independent influence of age, suicidal attempt and severe head injury on the outcomes of polytraumatized patients.

Keywords: epidemiology; outcome; polytrauma; sex differences.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
The influence of age (≥55 years of age) on the overall survival of 980 polytraumatized patients.
Figure 2
Figure 2
The influence of age and sex on the overall survival of 980 polytraumatized patients.

References

    1. Pape H.C., Lefering R., Butcher N., Peitzman A., Leenen L., Marzi I., Lichte P., Josten C., Bouillon B., Schmucker U., et al. The definition of polytrauma revisited: An international consensus process and proposal of the new ‘Berlin definition’. J. Trauma. Acute Care Surg. 2014;77:780–786. doi: 10.1097/TA.0000000000000453. - DOI - PubMed
    1. Butcher N., Balogh Z.J. AIS > 2 in at least two body regions: A potential new anatomical definition of polytrauma. Injury. 2012;43:196–199. doi: 10.1016/j.injury.2011.06.029. - DOI - PubMed
    1. GBD 2019 Diseases. Injuries Collaborators Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: A systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2020;396:1204–1222. doi: 10.1016/S0140-6736(20)30925-9. - DOI - PMC - PubMed
    1. Saad S., Mohamed N., Moghazy A., Ellabban G., El-Kamash S. Venous glucose, serum lactate and base deficit as biochemical predictors of mortality in patients with polytrauma. Ulus. Travma Acil Cerrahi Derg. 2016;22:29–33. doi: 10.5505/tjtes.2015.96832. - DOI - PubMed
    1. Tornetta P., 3rd, Mostafavi H., Riina J., Turen C., Reimer B., Levine R., Behrens F., Geller J., Ritter C., Homel P. Morbidity and mortality in elderly trauma patients. J. Trauma. 1999;46:702–706. doi: 10.1097/00005373-199904000-00024. - DOI - PubMed

LinkOut - more resources