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. 1986 Jan;165(1):312-4.
doi: 10.1128/jb.165.1.312-314.1986.

Transfer of chromosomal mutations to plasmids via Hfr-mediated conduction

C Park, G L Hazelbauer

Transfer of chromosomal mutations to plasmids via Hfr-mediated conduction

C Park et al. J Bacteriol. 1986 Jan.

Abstract

Nonconjugative plasmids can be transferred from an Hfr donor to a recipient by Hfr-mediated conduction. We found that this phenomenon can be employed to obtain a plasmid in which a mutation in a chromosomal gene has been transferred to the copy of that gene contained in the hybrid plasmid.

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References

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